Publication: Dental stem cells - characteristics and potential
Authors
Bojic, Sanja ; Volarevic, Vladislav ; Ljujic, Biljana ; Stojkovic, Miodrag
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Publisher
F. Hernández y Juan F. Madrid. Universidad de Murcia: Departamento de Biología Celular e Histología
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DOI
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info:eu-repo/semantics/article
Description
Abstract
Soft dental tissues have been identified as
easily accessible sources of multipotent postnatal stem
cells. Dental stem cells are mesenchymal stem cells
(MSC) capable of differentiating into at least three
distinct cell lineages: osteo/odontogenic, adipogenic and
neurogenic. They express various markers including
those specific for MSC, embryonic stem cells and neural
cells. Five different types of dental stem cells have been
isolated from mature and immature teeth: dental pulp
stem cells, stem cells from exfoliated deciduous teeth,
periodontal ligament stem cells, stem cells from apical
papilla and dental follicle progenitor cells. Dental stem
cells may be used in dental tissue engineering including
dental, enamel and periodontal tissue regeneration. They
could also be used as a promising tool in potential
treatment of neurodegenerative, ischemic and immune
diseases.
Citation
Histology and Histopathology, vol. 29, nº 6, (2014)
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