Publication: Morphogenesis and ultrastructure of the peripolar cells in the mouse kidney
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Date
1991
Authors
Sioga, A. ; Manthos, A. ; Economou, L. ; Foroglou, Ch.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
Peripolar cells are located in the outer layer
of the Bowman's capsule. They surround the vascular
pole of the renal corpuscle and project into the urinary
space. Morphologically they are characterized by the
presence of secretory granules within their cytoplasm. In
order to study their embryological development. we used
60 C57bl mice embryos (15th to 19th gestational day), 10
newborn mice (2 hours to 6 days old), 10 preadult mice
(8-30 days old) and 4 adults (4 months old). Some
granular cells, dispersed at the outer and inner layer of
the Bowman's capsule, appear on the 17th gestational
day. Later, these cells are found around the vascular pole
of the renal corpuscle, located exclusively at the outer
layer of the Bowman's capsule. Their granules are
spherical and variously dense, they are surrounded by a
membrane and their number increases progressively
with time and reaches a maximum on the 4th postnatal
day. Following that, there is a diminution and then
their population stabilizes. By the end of the first
month, there are only a few such cells (mean number
1 to 2). They become smaller and they always project
into the urinary space.
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