B-Scan ultrasonography of vitreous dynamics during intravitreal administration of antiangiogenics

Sánchez-Martínez, Daniel; Sánchez-López, Sara; Sellés-Navarro, Inmaculada

Publication:
B-Scan ultrasonography of vitreous dynamics during intravitreal administration of antiangiogenics

dc.contributor.author	Sánchez-Martínez, Daniel
dc.contributor.author	Sánchez-López, Sara
dc.contributor.author	Sellés-Navarro, Inmaculada
dc.contributor.department	Oftalmología, Optometría, Otorrinolaringología y Anatomía Patológica
dc.date.accessioned	2025-02-03T07:37:41Z
dc.date.available	2025-02-03T07:37:41Z
dc.date.issued	2021-11-01
dc.description	© by Ophthalmic Communications Society, Inc. 2021 This document is the published version of a published work that appeared in final form in Retina To access the final edited and published work see: https://doi.org/10.1097/IAE.0000000000003175
dc.description.abstract	Purpose: To study the distribution of angiogenesis inhibitors (anti-Vascular Endothelial Growth Factor) injected into the vitreous cavity by means of simultaneous ultrasonography. Methods: Three hundred and thirty-two B-scan ultrasound sequences of 121 eyes from 95 patients were recorded simultaneously to the intravitreal anti-Vascular Endothelial Growth Factor administration. The dynamics of the injected substance and the presence of reflux were studied, associating them with the presence/absence of total posterior vitreous detachment. Results: Three well-defined patterns were distinguished. Pattern A: the medication penetrates the vitreous in a linear manner until reaching the retina (3.6%, n = 12). Pattern B: the medication adopts a globular shape and then moves down reaching the retrohyaloid space (37%, n = 123). Pattern C: the medication remains in a globular form (54%, n = 180). The pattern was not identified in 17 (5.1%) injections. Pattern A was only observed in vitrectomized eyes. The reflux (7.8%) was exclusive in eyes showing a C pattern. A relationship (P < 0.001) was observed between the presence/absence of total posterior vitreous detachment, the patterns, and the presence of reflux. Conclusion: This study document for the first time the behavior of antiangiogenic medication injected into the vitreous cavity and how its distribution and the presence of reflux is conditioned by the previous state of the vitreous body.	es
dc.embargo.terms	1-ene-2999
dc.format	application/pdf	es
dc.format.extent	7	es
dc.identifier.citation	Retina 41(11):p 2325-2331, November 2021.
dc.identifier.doi	https://doi.org/10.1097/IAE.0000000000003175
dc.identifier.uri	http://hdl.handle.net/10201/149956
dc.language	eng	es
dc.publisher	Wolters Kluwer N.V.	es
dc.relation	Sin financiación externa a la Universidad	es
dc.relation.publisherversion	https://journals.lww.com/retinajournal/abstract/2021/11000/b_scan_ultrasonography_of_vitreous_dynamics_during.17.aspx	es
dc.rights.accessRights	info:eu-repo/semantics/restrictedAccess
dc.subject	Antiangiogenic therapies	es
dc.subject	Intravitreal medication
dc.subject	Ocular ultrasonography
dc.subject	Retinal drugs effects
dc.subject	Vitreous patterns
dc.subject	Vitreous reflux
dc.title	B-Scan ultrasonography of vitreous dynamics during intravitreal administration of antiangiogenics	es
dc.type	info:eu-repo/semantics/article	es
dspace.entity.type	Publication	es