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Seropathotypes, phylogroups, Stx subtypes and intimin types of Shiga toxin-producing Escherichia coli strains from wildlife animals with the same characteristics as human pathogenic isolates

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dc.contributor.authorMora Gutiérrez, Azucena
dc.contributor.authorLópez, Cecilia
dc.contributor.authorDhabi, Ghizlane
dc.contributor.authorLópez Beceiro, Ana M.
dc.contributor.authorFidalgo, Luís E.
dc.contributor.authorDíaz, Eduardo A.
dc.contributor.authorMartínez-Carrasco Pleite, Carlos
dc.contributor.authorMamani, Rosalía
dc.contributor.authorHerrera, Alexandra
dc.contributor.authorBlanco, Jesús E.
dc.contributor.authorBlanco, Miguel
dc.contributor.authorBlanco, Jorge
dc.contributor.departmentSanidad Animal
dc.contributor.otherFacultades de la UMU::Facultad de Veterinaria
dc.date.accessioned2026-01-07T09:46:58Z
dc.date.available2026-01-07T09:46:58Z
dc.date.copyright© 2012, American Society for Microbiology
dc.date.issued2012-02-03
dc.description.abstractThe objectives of this study were to investigate the presence of Shiga toxin-producing Escherichia coli (STEC) strains in wildlife that have spread in Europe, living near human settlements; to analyze their epidemiological role in maintenance and transmission to domestic livestock; and to assess the potential health risk of wildlife-carried strains. STEC strains were recovered from 53% of roe deer, 8.4% of wild boars, and 1.9% of foxes sampled in the northwest of Spain (Galicia). Of the 40 serotypes identified, 21 were classified as seropathotypes associated with human disease, accounting for 81.5% of the wildlife-carried STEC strains, including the enterohemorrhagic serotypes O157:H7-D-eae-γ1, O26:[H11]-B1-eae-β1, O121:H19-B1-eae-ε1, and O145:[H28]-D-eae-γ1. None of the wildlife-carried strains belonged to the highly pathogenic serotype O104:H4-B1 from the recent Germany outbreak. Forty percent of wildlife-carried STEC strains shared serotypes, phylogroups, intimin types, and Stx profiles with isolates from human patients from the same geographic area. Furthermore, wildlife-carried strains belonging to serotypes O5:HNM-A, O26:[H11]-B1, O76:H19-B1, O145:[H28]-D, O146:H21-B1, and O157:H7-D showed pulsed-field gel electrophoresis (PFGE) profiles with >85% similarity to human-pathogenic STEC strains. We also found a high level of similarity among STEC strains of serotypes O5:HNM-A, O26:[H11]-B1, and O145:HNM-D of bovine (feces and beef) and wildlife origins. Interestingly, O146:H21-B1, the second most frequently detected serotype in this study, is commonly associated with human diarrhea and isolated from beef and vegetables sold in Galicia. Importantly, at least 3 STEC isolates from foxes (O5:HNM-A-eae-β1, O98:[H21]-B1-eae-ζ1, and O146:[H21]-B1) showed characteristics similar to those of human STEC strains. In conclusion, roe deer, wild boar, and fox in Galicia are confirmed to be carriers of STEC strains potentially pathogenic for humans and seem to play an important role in the maintenance of STEC.
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dc.format.extent9
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dc.identifier.citationApplied and Environmental Microbiology, 2012, Vol. 78, N. 8 : 2578
dc.identifier.doihttps://doi.org/10.1128/AEM.07520-11
dc.identifier.eissn1098-5336
dc.identifier.issn0099-2240
dc.identifier.urihttp://hdl.handle.net/10201/183509
dc.languageeng
dc.publisherAmerican Society for Microbiology
dc.relationThis work was financially supported by grants AGL-2008-02129 (Ministerio de Ciencia e Innovación, Gobierno de España); 09TAL007261PR, 10MRU261023PR, and 2007/000044-0 (Xunta de Galicia and the European Regional Development Fund [ERDF]); and REIPI RD06/0008/1016-1018 and PS09/01273 (Ministerio de Ciencia e Innovación, Instituto de Salud Carlos III, Fondo de Investigación Sanitaria, Gobierno de España). Azucena Mora acknowledges the Ramón y Cajal program (Ministerio deCiencia e Innovación, Gobierno de España). Rosalía Mamani acknowledges the grant from the Agencia Española de Cooperación Internacional (AECI) (Ministerio de Asuntos Exteriores y de Cooperación, Gobierno de España).
dc.relation.publisherversionhttps://journals.asm.org/doi/10.1128/aem.07520-11
dc.rightsAttribution 4.0 International*
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectPhylogroups
dc.subjectStx subtypes and intimin types of Shiga toxin
dc.subjectEscherichia coli strains
dc.subjectHuman pathogenic isolates
dc.subjectWild mammals
dc.subjectSeropathotypes
dc.subject.odsObjetivo 15: Bosques, desertificación y diversidad biológica
dc.subject.odsObjetivo 3: Salud
dc.titleSeropathotypes, phylogroups, Stx subtypes and intimin types of Shiga toxin-producing Escherichia coli strains from wildlife animals with the same characteristics as human pathogenic isolates
dc.typeinfo:eu-repo/semantics/article
dc.type.versioninfo:eu-repo/semantics/acceptedVersion
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relation.isAuthorOfPublication74bbaf1b-2a73-4ec8-b1c6-429311688d3b
relation.isAuthorOfPublication.latestForDiscovery74bbaf1b-2a73-4ec8-b1c6-429311688d3b
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