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Histophilus somni: Pathogenicity in cattle. An update

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dc.contributor.authorPérez, D.S.es
dc.contributor.authorPérez, F.A.es
dc.contributor.authorBretschneider, G.
dc.date.accessioned2011-05-11T09:54:29Z
dc.date.available2011-05-11T09:54:29Z
dc.date.issued2010
dc.description.abstractHistophilus somni (H. somni) is a Gram-negative bacterium currently classified as a member of the Haemophilus-Actinobacillus-Pasteurella group. Clinical syndromes associated with H. somni infection involve thromboembolic meningoencephalitis, pneumonia and disease of the reproductive tract in cattle. Animals can be carriers of non-pathogenic variants of the organism, mainly in the genital mucosa. The causes of these differences in virulence between strains are not defined. Several determinants of virulence of the pathogen are proposed. However, many of these factors cannot be clearly related to clinical disease. H. somni avoids killing by phagocytic cells. Thus, it is able to evade the immune response by intracellular survival in the infected host. The bovine adaptive immune response against H. somni is not completely characterized. IgG2 antibodies are thought to be protective. However, the major antigen determinants of the bacterium are still unknown. Studies with H. somni bacterins have inconsistent results, especially because the factors involved in pathogenesis and immune response remain unclear.es
dc.formatapplication/pdfes
dc.format.extent17es
dc.identifier.issn1989-1784 (electrónico)es
dc.identifier.urihttp://hdl.handle.net/10201/20617
dc.languageenges
dc.publisherMurcia, Universidad de Murcia, Servicio de Publicacioneses
dc.relation.ispartofAnales de veterinaria de Murcia,es
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectHistophilus somnies
dc.subjectCattle
dc.subject.otherCDU::6 - Ciencias aplicadas::63 - Agricultura. Silvicultura. Zootecnia. Caza. Pesca::636 - Veterinaria. Explotación y cría de animales. Cría del ganado y de animales domésticos
dc.titleHistophilus somni: Pathogenicity in cattle. An updatees
dc.title.alternativeHistophilus somni: actualización de la patogenicidad en vacunoes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Anales de veterinaria de Murcia Vol. 26 (2010)