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Measurement of Trace Elements (Zinc, Copper, Magnesium, and Iron) in the Saliva of Horses: Validation Data and Changes in Equine Gastric Ulcer Syndrome (EGUS)

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dc.contributor.authorMuñoz-Prieto, Alberto
dc.contributor.authorCerón, José Joaquín
dc.contributor.authorTecles, Fernando
dc.contributor.authorCuervo, María Martín
dc.contributor.authorContreras-Aguilar, Maria Dolores
dc.contributor.authorAyala de la Peña, Ignacio
dc.contributor.authorOudada-Guillén, Adrián
dc.contributor.authorPardo-Marín, Luis
dc.contributor.authorHansen, Sanni
dc.contributor.departmentMedicina y Cirugía Animal
dc.date.accessioned2024-09-10T11:22:43Z
dc.date.available2024-09-10T11:22:43Z
dc.date.issued2024-06-07
dc.description© 2024. The authors. Once the embargo has passed, this document will be available under the CC-BY 4.0 license http://creativecommons.org/licenses/by /4.0/ This document is the published version of a published work that appeared in final form in Animals To access the final work, see DOI: https://doi.org/10.3390/ani14121724es
dc.description.abstractThe objective of this study was to evaluate the possible use of spectrophotometric assays for the measurement of trace elements, including Zinc (Zn), Copper (Cu), Magnesium (Mg), and iron (Fe) in the saliva of horses and study their possible changes in equine gastric ulcer syndrome (EGUS). EGUS is a highly prevalent disease, with a current high incidence due to the increase in intensive management conditions. There are two EGUS diseases: equine squamous gastric disease (ESGD) and equine glandular gastric disease (EGGD), which can appear individually or together. For this purpose, automated spectrophotometric assays for measuring these analytes in horse saliva were analytically validated. Then, these analytes were measured in the saliva of horses with only ESGD, only EGGD, both ESGD and EGGD and a group of healthy horses. The methods used to measure the analytes were precise and accurate. Horses diagnosed with EGGD presented significantly lower levels of Zn and Mg. Fe concentrations were significantly lower in the saliva of horses with ESGD and EGGD. Overall, these results indicate that there are changes in trace elements in saliva in EGUS that could reflect the physiopathological mechanisms involved in this process and open the possibility of using trace elements as biomarkers of this syndrome.es
dc.formatapplication/pdfes
dc.format.extent12es
dc.identifier.citationAnimals 2024, 14, 1724
dc.identifier.doihttps://doi.org/10.3390/ani14121724
dc.identifier.issnElectronic: 2076-2615
dc.identifier.urihttp://hdl.handle.net/10201/143791
dc.languageenges
dc.publisherMDPIes
dc.relationA.M.-P. was funded by a post-doctoral fellowship “Ramón y Cajal” (Ayuda RYC2021-033660-I financiada por MICIU/AEI/10.13039/501100011033 y por la Unión Europea NextGenerationEU/PRTR).es
dc.relation.publisherversionhttps://www.mdpi.com/2076-2615/14/12/1724es
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rightsAtribución 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectTrace elementses
dc.subjectHorseses
dc.subjectSalivaes
dc.subjectEGUSes
dc.titleMeasurement of Trace Elements (Zinc, Copper, Magnesium, and Iron) in the Saliva of Horses: Validation Data and Changes in Equine Gastric Ulcer Syndrome (EGUS)es
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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