Publication:
The protein acetyltransferase PatZ from Escherichia coli is regulated by autoacetylation-induced oligomerization

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dc.archivorevisadoAcetyl-CoA synthetase (Acs)
dc.contributor.authorCastaño Cerezo, Sara
dc.contributor.authorBernal Sanchez, Vicente
dc.contributor.authorManjón Rubio, Antonio
dc.contributor.authorFernández Espín, Vanesa
dc.contributor.authorGarcía de la Torre, José
dc.contributor.authorCánovas Díaz, Manuel
dc.contributor.authorDiego Puente, Teresa de
dc.contributor.authorGallego Jara, Julia
dc.contributor.departmentBioquímica y Biología Molecular B e Inmunología
dc.date.accessioned2023-12-12T23:11:57Z
dc.date.available2023-12-12T23:11:57Z
dc.date.issued2015
dc.description©2015. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ This document is the Accepted version of a Published Work that appeared in final form in Journal of Biological Chemistry (JBC). To access the final edited and published work see http://www.jbc.org/cgi/doi/10.1074/jbc.M115.649806
dc.description.abstractBackground: PatZ is the main Escherichia coli acetyltransferase and control acetyl-CoA synthetase (Acs) activity. Results: The kinetic and structural PatZ oligomer characteristics were determined. Conclusion: PatZ is a stable tetramer and forms an active octamer by autoacetylation to increase its stability. Significance: PTMs by acetylation have structural and functional roles in the cell.
dc.formatapplication/pdfes_ES
dc.format.extent33
dc.identifier.citationJournal of Biological Chemistry (JBC)
dc.identifier.doihttp://www.jbc.org/cgi/doi/10.1074/jbc.M115.649806
dc.identifier.issn0021-9258
dc.identifier.urihttp://hdl.handle.net/10201/136586
dc.languageenges_ES
dc.relation.isreferencedbyED_IDENTRADA=1277
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectAcetyltransferase
dc.subjectPost-translational modification (PTM)
dc.subjectAcetyl coenzyme A (acetyl-CoA)
dc.subjectEscherichia coli (E. coli)
dc.subjectLysine acetylation
dc.subjectAutoacetylation
dc.subjectOligomerization
dc.subjectProtein acetyltransferase (PatZ or YfiQ)
dc.titleThe protein acetyltransferase PatZ from Escherichia coli is regulated by autoacetylation-induced oligomerizationes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dspace.entity.typePublicationes
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relation.isAuthorOfPublicationb8be181a-7224-475a-8427-543751ef593c
relation.isAuthorOfPublication0212fc0f-e15c-4b27-9a2d-116768a47044
relation.isAuthorOfPublication.latestForDiscovery57bf3537-1124-49ab-8774-bd0c3bdf1c28
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