Publication: MiRNAs participate in the diagnosis, pathogenesis and therapy of Parkinson's disease
Authors
Lu, Xuexin ; Cui, Zhijie ; Liu, Shuang ; Yin, Feng
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Publisher
Universidad de Murcia. Departamento de Biología Celular e Histología
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DOI
DOI: 10.14670/HH-11-944
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info:eu-repo/semantics/article
Description
Abstract
MicroRNAs (miRNAs), one kind of posttranscriptional modification, mediate transcriptional
silencing of various metabolic enzymes that are involved
in various life processes, including Parkinson’s disease.
At present, the pathogenesis of Parkinson's disease is not
clear, although many studies suggest that miRNAs play a
very important role in the progress of Parkinsonism.
This paper reviews the biological characteristics of
miRNAs and summarizes the progress of miRNAs in
reference to the diagnosis and pathogenesis of
Parkinson’s disease. It even considers miRNAs as a
potential target for Parkinson’s disease therapy
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Citation
Histology and Histopathology, Vol.33, nº5, (2018)
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