Publication: Effects of the relationship between 65Zn and
blood cells. A dynamic and morphological study
Authors
Vera-Gil, A. ; Pérez Castejón, M.J. ; Whyte, J. ; Cisneros, A. ; Recreo, P. ; Gascón, M.A. ; Whyte, A. ; Lahoz, M. ; Pérez Castejón, M.C.
item.page.secondaryauthor
item.page.director
Publisher
F. Hernández y Juan F. Madrid. Universidad de Murcia. Departamento de Biología Celular e Histología
publication.page.editor
publication.page.department
DOI
item.page.type
info:eu-repo/semantics/article
Description
Abstract
We have studied the dynamic pathway of
65Zn and its autoradiographic location in blood cells,
even at the ultra-structural level. We have found
evidence that tends to confirm the old biochemical
postulates about the capacity of this isotope to displace
iron in the haemoglobin molecule.
Recently, the bibliography has demonstrated that
57Co is also able to perform this displacement, but unlike
65Zn it does not invalidate the Redox function of the
molecule.
In the case of 65Zn, the mentioned displacement
invalidates this function because the radionuclide can
only use valence 2. We have also contributed evidence
of erythrocytes destruction by the spleen after the
incorporation of 65Zn, as well as the clearly marked
degradation of haematic pigments inside the spleen.
publication.page.subject
Citation
Histology and Histopathology, vol. 28, nº 8 (2013)
item.page.embargo
Ir a Estadísticas
Sin licencia Creative Commons.