Publication: Extra-meningeal solitary fibrous tumor: an evolving entity with chameleonic morphological diversity, a hallmark molecular alteration and unresolved issues in risk stratification assessment
Authors
Machado, Isidro ; Giner, Francisco ; Cruz, Julia ; Lavernia, Javier ; Marhuenda Fluixa, Ana ; Claramunt, Reyes ; López Guerrero, José Antonio ; Navarro, Samuel ; Ferrandez, Antonio ; Blázquez Bujeda, Álvaro ; Ruiz-Sauri, Amparo ; Llombart Bosch, Antonio
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Publisher
Universidad de Murcia. Departamento de Biología Celular e Histología
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DOI
https://doi.org/10.14670/HH-18-608
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info:eu-repo/semantics/article
Description
Abstract
Solitary fibrous tumor (SFT) is a rare type of
mesenchymal lesion with variable clinical presentation
in which specific clinicopathologic factors have been
related to patient outcome. SFT shares an important
morphologic and immunohistochemical overlap with
other sarcomas, hence the differential diagnosis is
challenging. Although molecular studies provide
significant clues, especially in the differential diagnosis
with other neoplasms, a thorough hematoxylin and eosin
analysis and the integration of phenotypical, clinical, and
radiological features remain an essential tool in SFT
diagnosis. In this review, we discuss some emerging
issues still under debate in SFT.
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Citation
Histol Histopathol, Vol.38, nº10, (2023)
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