Publication:
Acetyl-and butyrylcholinesterase activities decrease in human colon adenocarcinoma

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dc.contributor.authorMontenegro Arce, María Fernanda
dc.contributor.authorRuiz Espejo, Francisco
dc.contributor.authorCampoy Menéndez, Francisco Javier
dc.contributor.authorMuñoz Delgado, Encarnación
dc.contributor.authorPáez de la Cadena, María
dc.contributor.authorCabezas Herrera, Juan
dc.contributor.authorVidal, Cecilio J.
dc.contributor.departmentBioquímica y Biología Molecular A
dc.date.accessioned2026-02-23T12:31:57Z
dc.date.available2026-02-23T12:31:57Z
dc.date.copyright© 1969, Humana Press Inc.
dc.date.issued2006-02
dc.description.abstractApart from the hydrolysis of acetylcholine (ACh), acetyl- (AChE) and butyrylcholinesterase (BChE), through noncatalytic mechanisms, intervene in hematopoiesis, morphogenesis, and neurogenesis (Layer and Willbold, 1995; Soreq and Seidman, 2001). Cholinesterase (ChE) molecules occur as globular (G1, G2, and G4) and asymmetric (A4, A8, and A12) forms (Legay, 2000; Massoulié, 2002). The G species might display amphiphilic (GA) or hydrophilic (GH) properties (Perrier et al., 2002). The involvement of ChEs in tumorigenesis is supported by the measurement of ChE activity in tumors (García-Ayllón et al., 2001; Ruiz-Espejo et al., 2003), the amplification of ChE genes in leukemias and ovarian tumors, and the relationship between the expression of AChE and the aggressiveness of astrocytomas(Perry et al., 2002). This research was undertaken to determine whether ChE activity is altered in gut carcinomas.
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dc.format.extent7
dc.identifier.citationJournal of Molecular Neuroscience, 30, 51–53 (2006)
dc.identifier.doihttps://doi.org/10.1385/jmn:30:1:51
dc.identifier.eissn1559-1166
dc.identifier.issn0895-8696
dc.identifier.urihttp://hdl.handle.net/10201/210741
dc.languageeng
dc.publisherSpringer
dc.relationFondo de Investigación Sanitaria of Spain (Grant PI041504) and the Fundación Séneca of Murcia (Grant 00636/PI/04).
dc.relation.publisherversionhttps://link.springer.com/article/10.1385/JMN:30:1:51
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectAChE
dc.subjectBuChE
dc.subjectAdenocarcinoma
dc.subjectCancerous Colorectal
dc.subjectCholinesterase
dc.subjectMolecular neuroscience volume
dc.subjectChEs
dc.subjectHuman colon adenocarcinoma
dc.subject.odsObjetivo 3: Salud
dc.titleAcetyl-and butyrylcholinesterase activities decrease in human colon adenocarcinoma
dc.typeinfo:eu-repo/semantics/article
dc.type.versioninfo:eu-repo/semantics/acceptedVersion
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