Publication: Cell types in the central nervous system infected by murine retroviruses: implications for the mechanisms of neurodegeneration
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Date
1994
Authors
Wong, P.K.Y. ; Yuen, P.H.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
Retroviruses are an important cause of
neurologic disease in humans but the pathogenic
mechanisms are poorly understood. To delineate
pathogenic mechanisms in any neurologic disease in
humans is extremely difficult and will continue to rely
on the use of animal models. This review presents
severa1 murine models to study the pathogenic
mechanisms of neurodegenerative disease which
manifest noninflammatory spongiform lesions in the
CNS. The cell types in the CNS infected by these murine
retroviruses and their role in disease induction are
discussed.
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Citation
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