Pyostomatitis vegetans. Report of two cases and review of the literature

Ruiz Roca, Juan Antonio; Berini Aytés, Leonardo; Gay Escoda, Cosme

Publication:
Pyostomatitis vegetans. Report of two cases and review of the literature

dc.contributor.author	Ruiz Roca, Juan Antonio
dc.contributor.author	Berini Aytés, Leonardo
dc.contributor.author	Gay Escoda, Cosme
dc.contributor.department	Dermatología, Estomatología, Radiología y Medicina Física
dc.contributor.other	Facultades de la UMU::Facultad de Medicina
dc.date.accessioned	2026-03-25T07:37:20Z
dc.date.available	2026-03-25T07:37:20Z
dc.date.copyright	© 2005 Elsevier Inc.
dc.date.issued	2005-04
dc.description.abstract	Pyostomatitis vegetans (PV) is a rare benign chronic mucocutaneous pustular disorder of unknown etiology, though it is usually associated with chronic inflammatory disease of the bowel—particularly ulcerative colitis. At the oral level PV manifests as an exophytic lesion with an erythematous perimeter and a creamy-yellow surface presenting a friable covering membrane which easily disintegrates, giving rise to the development of small ulcers or superficial erosions. The histology shows epithelial acanthosis and superficial ulceration. The underlying connective tissue exhibits neutrophil and eosinophil infiltration, with miliary abscesses in some cases. The present study describes 2 cases of PV associated with ulcerative colitis. The differential diagnosis should be established with Neumann type pemphigus vegetans, since in both cases the lesions are clinically similar and the histology reveals an important eosinophil response, acanthosis, and the formation of intraepithelial miliary microabscesses. The treatment of PV focuses on control of the disease. In the event the orofacial lesions persist, topical oral drugs such as corticoids, with additional antibiotherapy, multivitamin complexes, and nutritional supplements, can be provided.
dc.format	application/pdf
dc.format.extent	8
dc.identifier.citation	Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, Volume 99, Issue 4, April 2005, Pages 447-454
dc.identifier.doi	https://doi.org/10.1016/j.tripleo.2003.08.022
dc.identifier.eissn	2212-4411
dc.identifier.issn	2212-4403
dc.identifier.uri	http://hdl.handle.net/10201/222662
dc.language	eng
dc.publisher	Elsevier
dc.relation	Sin financiación externa a la Universidad
dc.relation.publisherversion	https://www.sciencedirect.com/science/article/pii/S1079210403005304
dc.rights.accessRights	info:eu-repo/semantics/restrictedAccess
dc.subject.ods	No relacionado con ningún objetivo de desarrollo sostenible
dc.title	Pyostomatitis vegetans. Report of two cases and review of the literature
dc.type	info:eu-repo/semantics/article
dc.type.version	info:eu-repo/semantics/publishedVersion
dspace.entity.type	Publication	es
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