Publication: A case study of ligation induced calcification in middle cerebral artery in rat
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Date
2000
Authors
Tseng, M.T. ; Chan, S.A. ; Guo, S.Z.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
A 90 rnin ligation of the middle cerebral artery
(MCA) followed by 72-hour reperfusion appeared to
cause calcium deposition in vascular myocytes of the
tunica media and thc pcrivascular tissue 01 the Sprague
Dawley rat. The presence of small ovoid to large
irregularly shaped intracellular opaque dcposits were
demonstrated by light and electron microscopy. Using
X-ray elemental analysis the chemical nature of the
deposits was found to be calcium phosphate. The
functional significance of this first demonstration of
acute calcification following transient ligation of the
rodent MCA invites further studies.
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Citation
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