CD26 dipeptidyl peptidase IV and its role in cancer

Publication:
CD26 dipeptidyl peptidase IV and its role in cancer

dc.contributor.author	Pro, B.	es
dc.contributor.author	Dang, N.H.	es
dc.date.accessioned	2011-06-08T09:09:49Z
dc.date.available	2011-06-08T09:09:49Z
dc.date.issued	2004
dc.description.abstract	CD26/Dipeptidyl Peptidase IV (DPPIV) is a 110-kDa glycoprotein that is expressed on numerous cell types and has multiple biological functions. A key facet of CD26/DPPIV biology is its enzymatic activity and its physical and functional interaction with other molecules. The substrates of CD26/DPPIV are proline-containing peptides and include growth factors, chemokines, neuropeptides, and vasoactive peptides. DPPIV plays an important role in immune regulation, signal transduction, and apoptosis. Furthermore, CD26 appears to play an important role in tumor progression. In the present review, we summarize key aspects of CD26/DPPIV involvement in tumor biology and its potential role in cancer development and behavior.	es
dc.format	application/pdf	es
dc.format.extent	7	es
dc.identifier.issn	0213-3911	es
dc.identifier.uri	http://hdl.handle.net/10201/21644
dc.language	eng	es
dc.publisher	Murcia : F. Hernández	es
dc.relation.ispartof	Histology and histopathology	es
dc.rights	info:eu-repo/semantics/openAccess	es
dc.subject	Cancer	es
dc.subject	Targeted therapy	es
dc.subject.other	CDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología	es
dc.title	CD26 dipeptidyl peptidase IV and its role in cancer	es
dc.type	info:eu-repo/semantics/article	es
dspace.entity.type	Publication	es

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