Publication: Time course variations of antioxidant enzyme activities and histopathology of
gilthead seabream gills exposed to malathion
Authors
Rosety, M.A. ; Rosety-Rodriguez, M. ; Ordóñez Muñoz, F.J. ; Rosety, I.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
In a widely distributed and commercially
important fish, gilthead seabream Sparus aurata L., we
have studied sublethal effects of malathion in order to
identify early warning bioindicators of exposure before
irreversible damage occurs.
To achieve this goal, groups of 10 juvenile
specimens were exposed for 24, 48, 72 and 96h to a
sublethal concentration of malathion (0.4 mg/l). Another
group was used as control. The activity of antioxidant
enzymes (superoxide dismutase, catalase and glutathione
peroxidase) and histopathological features from exposed
gills were assessed. It should also be mentioned that no
mortality was observed during the whole experience.
The activity of superoxide dismutase (SOD),
catalase (CAT) and glutathione peroxidase (GPX) were
altered significantly from 24 h onward (p<0.05). It is of
interest to note that catalase activity was decreased after
exposure instead of increasing as other antioxidant
enzymes assessed. On the other hand, histopathological
alterations of the gills were observed as early as at 48 hexposure,
but the most severe damage occurred at 96 h
exposure.
The evidence presented here, together with other
data from the literature, unequivocally established oxidative-stress-inducing effects of malathion in gilthead
seabream Sparus aurata. It is also concluded
antioxidants employed (SOD, CAT and GPX) changed
significantly a long time before histopathological
alterations of gills became evident. Consequently, these
antioxidant enzymes may be highly recommended as
early-warning bioindicators of environmental pollution
by malathion in the areas where it is proposed to be used
in pest control activities.
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