Publication:
Thrombocytopenia in leukemia: Pathogenesis and prognosis

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dc.contributor.authorShahrabi, Saeid
dc.contributor.authorMaleki Behzad, Masumeh
dc.contributor.authorJaseb, Kaveh
dc.contributor.authorSaki, Najmaldin
dc.date.accessioned2022-05-18T11:37:25Z
dc.date.available2022-05-18T11:37:25Z
dc.date.issued2018
dc.description.abstractLeukemias, a heterogeneous group of hematological disorders, are characterized by ineffective hematopoiesis and morphologic abnormalities of hematopoietic cells. Thrombocytopenia is a common problem among leukemia types that can lead to hemorrhagic complications in patients. The purpose of this review article is to identify the conditions associated with the incidence of thrombocytopenia in leukemias. It can be stated that although translocations have been considered responsible for this complication in many studies, other factors such as bone marrow failure, genes polymorphism, a mutation in some transcription factors, and the adverse effects of treatment could be associated with pathogenesis and poor prognosis of thrombocytopenia in leukemias. Considering the importance of thrombocytopenia in leukemias, it is hoped that the recognition of risk factors increasing the incidence of this complication in leukemic patients would be useful for prevention and treatment of this disorder.es
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dc.format.extent14es
dc.identifier.citationHistology and Histopathology, Vol.33, nÂş9, (2018)
dc.identifier.doiDOI: 10.14670/HH-11-976
dc.identifier.issn1699-5848
dc.identifier.issn0213-3911
dc.identifier.urihttp://hdl.handle.net/10201/120172
dc.languageenges
dc.publisherUniversidad de Murcia. Departamento de BiologĂ­a Celular e HistologĂ­aes
dc.relationSin financiaciĂłn externa a la Universidades
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectLeukemiaes
dc.subjectThrombocytopeniaes
dc.subjectPolymorphismes
dc.subjectMutationes
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::616 - PatologĂ­a. Medicina clĂ­nica. OncologĂ­aes
dc.titleThrombocytopenia in leukemia: Pathogenesis and prognosises
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.33, nÂş9 (2018)