Publication: Gastric intestinal metaplasia eleven years after randomized selective proximal vagotomy for peptic ulcer
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Date
1993
Authors
Rubio, C.A. ; Emas, S. ; Slezak, P. ; Nakano, H. ; Kalin, B.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
The presence of intestinal metaplasia (IM) 11
years after selective proximal vagotomy (SPV), selective
proximal vagotomy with pyloroplasty (SPV + PP) and
selective vagotomy with pyloroplasty (SV + PP) was
investigated in 38 consecutive patients. IM was
significantly more frequent in SPV than in SV + PP,
SPV + PP or in unoperated controls of matching ages.
IM occurred more frequently both at an older age (260
years) in SPV and in a larger number of gastric areas
than in the other group of patients. Reports in the
literature indicate that vagotomy may increase the risk of
gastric carcinoma and that IM inay antedate malignant
transformation. It would thus appear that patients
previously operated with SPV (without pyloroplasty)
having IM, should be the group of patients to be enrolled
in endocospical surveillance programs for detection of
possible cancer development.
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