Publication: Tolerance and adherence of patients with chronic chagas disease treated with benznidazole
Authors
Vázquez, Cristina ; García-Vázquez, Elisa ; Carrilero, Bartolomé ; Simón, Marina ; Franco, Fuensanta ; Iborra, María Asunción ; Gil-Gallardo, Luis Javier ; Segovia, Manuel
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Publisher
Sociedade Brasileira de Medicina Tropical
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DOI
https://doi.org/10.1590/0037-8682-0384-2022
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info:eu-repo/semantics/article
Description
©2023 Sociedade Brasileira de Medicina Tropical. This manuscript version is made available under the CC-BY 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ . This document is the Published, version of a Published Work that appeared in final form in Journal of the Brazilian Society of Tropical Medicine . To access the final edited and published work see https://doi.org/10.1590/0037-8682-0384-2022
Abstract
Background: Chagas disease (CD) treatment is commonly associated with a high incidence of adverse effects. It is crucial to study and update these adverse effects to improve the existing knowledge of which drugs to use and to clarify the information presented to patients.
Methods: We analyzed the adverse effects of benznidazole in two cohorts of patients: a large retrospective study and a small prospective study.
Results: This large retrospective study described the most and least common adverse effects in our area and characterized our Chagas disease population. This prospective study, along with a close follow-up of the treatment, detected more adverse effects and enhanced the patients’ perception of the disease and treatment.
Conclusions: This information is important for preventing non-medical-related withdrawals and for removing baseless fears. Better knowledge of patients could help us provide better care.
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Citation
Journal of the Brazilian Society of Tropical Medicine, Vol.:56 | (e0384-2022) | 2023
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