Publication:
Accuracy of anogenital distance and anti-Müllerian hormone in the diagnosis of endometriosis without surgery

Simple item page
dc.contributor.authorSánchez-Ferrer María L.
dc.contributor.authorJiménez-Velázquez, Raquel
dc.contributor.authorMendiola, Jaime
dc.contributor.authorPrieto-Sánchez, María T.
dc.contributor.authorCánovas-López, Laura
dc.contributor.authorCarmona-Barnosi, Ana
dc.contributor.authorCorbalán-Biyang, Shiana
dc.contributor.authorHernández-Peñalver, Ana I.
dc.contributor.authorAdoamnei, Evdochia
dc.contributor.authorNieto, Aníbal
dc.contributor.authorTorres-Cantero, Alberto M.
dc.contributor.departmentCirugía, Pediatría y Obstetricia y Ginecología
dc.contributor.departmentCiencias Sociosanitarias
dc.date.accessioned2024-02-12T08:41:10Z
dc.date.available2024-02-12T08:41:10Z
dc.date.issued2019
dc.description©<2019>. This manuscript version is made available under the CC-BY-NC 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ This document is the, Accepted, version of a Published Work that appeared in final form in International Journal of Gynecology & Obstetrics. To access the final edited and published work see: https://doi.org/10.1002/ijgo.12691
dc.description.abstractObjective: To assess the predictive ability of a combination of anogenital distance (AGD) and anti-Müllerian hormone (AMH) to diagnosis the presence of endometriosis without surgery. Methods: The present study included women diagnosed with endometriosis and a control group who attended the "Virgen de la Arrixaca" University Hospital, Murcia, Spain, between September 1, 2014, and May 31, 2015. Serum concentrations of AMH were measured, and two AGD measurements were obtained: from the anterior clitoral surface to the upper verge of the anus (AGDAC ), and from the posterior fourchette to the upper verge of the anus (AGDAF ). Data were assessed by receiver operator characteristic (ROC) curves. Results: Women in the endometriosis group (n=57) had significantly shorter AGDAF (22.8 ± 4.6 vs 27.2 ± 5.7 mm; P<0.001) and lower AMH (2.2 ± 2.5 vs 3.3 ± 1.9 ng/mL; P<0.003) compared with the control group (n=93). Women with serum AMH below the clinical cut-off (1 ng/mL) were 17.40-times more likely to have endometriosis (95% confidence interval [CI] 5.64-53.82). The area under the ROC curve of combined AMH and AGDAF was 0.77 (95% CI 0.70-0.85). Conclusion: The model for predicting endometriosis on the basis of AMH and AGD could be useful for clinicians and epidemiologists to improve diagnosis and prognosis of this condition.en
dc.formatapplication/pdfes
dc.format.extent22es
dc.identifier.citationInternational Journal of Gynaecology and Obstetrics. 2019 Jan 144(1):90-96
dc.identifier.doihttps://doi.org/10.1002/ijgo.12691
dc.identifier.issnPrint: 0020-7292
dc.identifier.issnElectronic: 1879-3479
dc.identifier.urihttp://hdl.handle.net/10201/139235
dc.languageenges
dc.publisherWiley
dc.relationThe present study was supported by the Ministry of Economy and Competitiveness, ISCIII (grant no. PI13/01237), and the Seneca Foundation, Murcia Regional Agency of Science and Technology (grant no. 19443/PI/14).es
dc.relation.requireshttps://doi.org/10.1002/ijgo.12691es
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectAnogenital distanceen
dc.subjectAnti-Müllerian hormoneen
dc.subjectEndometriosisen
dc.subjectPredictive modelen
dc.subjectPrenatal exposuresen
dc.subjectROC curveen
dc.titleAccuracy of anogenital distance and anti-Müllerian hormone in the diagnosis of endometriosis without surgeryes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
in press.pdf
Size:
364.71 KB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
2.26 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Artículos