Publication:
Heart matters: cardiac dysfunction and other autonomic changes in Parkinson’s disease

dc.contributor.authorGonçalves, Valeria C.
dc.contributor.authorCuenca Bermejo, Lorena
dc.contributor.authorFernández Villalba, Emiliano
dc.contributor.authorMartin Balbuena, Sebastian
dc.contributor.authorFernandes, Maria Jose da Silva
dc.contributor.authorScorza, Carla A.
dc.contributor.authorHerrero Ezquerro, María Trinidad
dc.contributor.departmentMedicina
dc.contributor.otherFacultades de la UMU
dc.date.accessioned2026-01-12T08:59:16Z
dc.date.available2026-01-12T08:59:16Z
dc.date.copyright© The Author(s) 2021.
dc.date.issued2021-02-15
dc.description.abstractIt has been more than 200 years since James Parkinson made the first descriptions of the disease that bears his name. Since then, knowledge about Parkinson’s disease has been improved, and its pathophysiology, diagnosis, and treatments are well described in the scientific and medical literature. However, there is no way to prevent the disease from its progressive nature yet and only its symptoms can be minimized. It is known that the process of neurodegeneration begins before the onset of motor signs and symptoms of the disease, when diagnosis is usually made. Therefore, recognizing manifested non-motor symptoms can make an early diagnosis possible and lead to a better understanding of the disease. Autonomic dysfunctions are important non-motor manifestations of Parkinson’s disease and affect the majority of patients. Importantly, heart failure is the third leading cause of death in people suffering from Parkinson’s disease. Several evidences have shown the correlation between Parkinson’s disease and the preexistence of cardiovascular diseases. Therefore, cardiovascular monitoring and identification of its dysfunctions can have a prodromal role for Parkinson’s disease. This review presents studies of the literature that can lead to a better understanding of Parkinson’s disease with special attention to its relation to heart and cardiovascular parameters.
dc.formatapplication/pdf
dc.identifier.citationThe Neuroscientist, 2022, Vol. 28, Issue 6, pp. 530 - 542
dc.identifier.doihttps://doi.org/10.1177/1073858421990000
dc.identifier.eissn1089-4098
dc.identifier.issn1073-8584
dc.identifier.urihttp://hdl.handle.net/10201/185649
dc.languageeng
dc.publisherSAGE Publications
dc.relationFundación Séneca(19540/PI/1 4) y CNPq Process 302583/2017-3. VCG fue becada por CAPES (88882330550/2019-01) y recibió una CAPES-Print scholarship (88887469009/2019-00). LC-B fue becada por el ministerio de Ciencia, Innovación y Universidades (FPU 18/02549).
dc.relation.publisherversionhttps://journals.sagepub.com/doi/10.1177/1073858421990000
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectNeurodegeneration
dc.subjectHeart
dc.subjectCardiovascular
dc.subjectDysautonomia
dc.subjectParkinson’s disease
dc.subject.odsObjetivo 3: Salud
dc.titleHeart matters: cardiac dysfunction and other autonomic changes in Parkinson’s disease
dc.typeinfo:eu-repo/semantics/article
dc.type.versioninfo:eu-repo/semantics/acceptedVersion
dspace.entity.typePublicationes
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relation.isAuthorOfPublication072da45c-404e-4559-a637-6e8df94220c7
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relation.isAuthorOfPublication.latestForDiscovery80cb2f28-f9ff-4190-8ac0-a4773288c0d3
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