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Salivary adiponectin, but not adenosine deaminase, correlates with clinical signs in women with Sjögren’s syndrome: a pilot study

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dc.contributor.authorTvarijonaviciute, Asta
dc.contributor.authorZamora, Carmen
dc.contributor.authorMartinez-Subiela, Silvia
dc.contributor.authorTecles, Fernando
dc.contributor.authorPina, Francisca
dc.contributor.authorLopez Jornet, Pia
dc.contributor.departmentDermatología, Estomatología, Radiología y Medicina Física
dc.date.accessioned2024-01-29T07:56:07Z
dc.date.available2024-01-29T07:56:07Z
dc.date.issued2018-07-20
dc.description© 2018. The authors. This document is the Published version of a published Work that appeared in final form in Clinical Oral Investigations. To access the final edited and published work see https://doi.org/10.1007/s00784-018-2570-3es
dc.description.abstractObjectives To evaluate salivary adiponectin and adenosine deaminase (ADA) in women suffering from Sjögren’s syndrome (SS). Methods Salivary adiponectin and ADA were measured in patients with SS (n = 17) and compared to their values in healthy controls (n = 13) and patients suffering from drug-induced xerostomia (non-SS sicca group; n = 19). A clinical history was made for each patient, patients were examined clinically, and xerostomia inventory (XI) was performed. Results Salivary adiponectin corrected by total protein was higher in patients with SS than in healthy individuals (P < 0.05) or patients with non-SS sicca (P < 0.01) and correlated with XI (r = 0.555; P < 0.05). Salivary ADAwas higher in patients with SS and non-SS sicca compared to controls (P<0.05 in both cases). Conclusion The results of the present study indicate that adiponectin and ADA are increased in the saliva of patients with SS. Clinical relevance Salivary adiponectin corrected by total protein can be a potential biomarker of SS.es
dc.embargo.terms1-ene-2999
dc.formatapplication/pdfes
dc.format.extent8es
dc.identifier.citationClinical Oral Investigations (2019) 23:1407–1414
dc.identifier.doihttps://doi.org/10.1007/s00784-018-2570-3
dc.identifier.issnPrint: 1432-6981
dc.identifier.issnElectronic: 1436-3771
dc.identifier.urihttp://hdl.handle.net/10201/137899
dc.languageenges
dc.publisherhttps://link.springer.com/es
dc.relationAsta Tvarijonaviciutewas financially supported by the Program BJuan de la Cierva Incorporacion^ of BMinisterio de Economia y Competitividad,^ Spain, through a post-doctoral grant.es
dc.relation.publisherversionhttps://link.springer.com/article/10.1007/s00784-018-2570-3es
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectAdiponectines
dc.subjectAdenosine deaminasees
dc.subjectBiomarkeres
dc.subjectClinical signses
dc.subjectXerostomiaes
dc.subjectSalivaes
dc.subject.otherInterdisciplinary Laboratory of Clinical Analysis Interlab-UMU, Faculty of Veterinary / Facultad de Medicina Odontologia Medicine,es
dc.titleSalivary adiponectin, but not adenosine deaminase, correlates with clinical signs in women with Sjögren’s syndrome: a pilot studyes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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