Publication: Distribution of central catecholaminergic neurons, a comparison between ungulates, humans and other species
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Date
1998
Authors
Tillet, Y. ; Kitahama, K.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
In ungulates and primates, the distribution of
central catecholaminergic neurons identified using
antibodies raised against catecholamine synthesizing
enzymes and catecholamines themselves, shows many
differences if compared to rats. Catecholaminergic
neurons are more loosely clustered in ungulates and
primates than in rat. In the medulla oblongata, the
density of noradrenergicladrenergic neurons is lower in
ungulates than in other species and, particularly in sheep,
the adrenergic group C1 is not observed. The noradrenergic
neurons of the locus coeruleus are present in
a larger area in ungulates than in rodents. In the
hypothalamus, the density of dopamine neurons is lower
in ungulates and primates than in rodents. In the rostra1
hypothalamus of ungulates, the dorsal part of the group
A14 is missing, and these species present only the
ventral part of the group A15. In primates the group A15
extends into the supraoptic and paraventricular nuclei
which have large tyrosine hydroxylase-immunoreactive
(TH-IR) neurons not observed in other species. In
addition, in all studied species, not all cells expressing
catecholamine synthesizing enzymes also express
catecholamines, as found in some TH-IR neurons in the
arcuate nucleus, thereby demonstrating the necessity of
using different markers to ascertain the true catecholaminergic
nature of labeled neurons. These anatomical
differences between species show the difficulty in
extrapolating the distribution of catecholamine neurons
from one species to another and may be related
to adaptative physiological differences between
mammals.
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