Publication: Experimental vasectomy and testicular structure
Authors
Sarrat, R. ; Whyte, J. ; Torres, A. ; Lostalé, F. ; Díaz, Mª.P.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
We have performed an experimental study on
rats and dogs to evaluate the long term effects (from 1 to
12 months) of vasectomy on the structure of the testis.
From four months after vasectomy onwards, the
specimens showed very important changes in the
seminiferous epithelium and Sertoli cells, with an
obvious thickening of the basement membrane that
supports the epithelium. The deterioration depended on
the time passed and, over six months after vasectomy,
the alterations were very clear and the seminiferous
tubules became atrophic and shnink, sometimes without
any remains of seminiferous epithelium and with an
important hypertrophy of the interlobular interstitial
tissue, although we did not see an increase in the number
of Leydig cells.
Alterations due to vasectomy depend on the animal
species, the peculiarities of techniques and, of course,
the time passed after surgery.
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