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Different expression of the catalytic alpha subunits of the AMP activated protein kinase - an immunohistochemical study in human tissue

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dc.contributor.authorQuentin, Thomas
dc.contributor.authorKitz, Julia
dc.contributor.authorSteinmetz, Michael
dc.contributor.authorPoppe, Andrea
dc.contributor.authorBär, Karin
dc.contributor.authorKrätzner, Ralph
dc.coverage.spatialAlemaniaes
dc.coverage.temporal2009es
dc.date.accessioned2016-04-14T11:25:50Z
dc.date.available2016-04-14T11:25:50Z
dc.date.issued2011
dc.description.abstractSummary. AMPK is an ubiquitously distributed multienzyme complex. It is an important energy sensor and regulator of cellular metabolic activity. In this study we analyzed for the first time the cellular distribution of the catalytically active subunits AMPKα1 and α2 in different human tissues by immunohistochemistry. We found different expression patterns for both isoforms. AMPKα2 expression clearly dominates in skeletal myocytes and cardiomyocytes, whereas AMPKα1 dominates in a number of secreting cells, like mammary glands, islets of langerhans and cells of the colon crypts.es
dc.formatapplication/pdfes
dc.format.extent8es
dc.identifier.issn1699-5848
dc.identifier.issn0213-3911
dc.identifier.urihttp://hdl.handle.net/10201/48593
dc.languageenges
dc.publisherMurcia: F. Hernándezes
dc.relation.ispartofHistology and Histopathology, vol.26, 2011es
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectAMPKes
dc.subjectImmunohistochemistryes
dc.subjectSecretiones
dc.subject.other61 - Medicinaes
dc.titleDifferent expression of the catalytic alpha subunits of the AMP activated protein kinase - an immunohistochemical study in human tissuees
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.26, nº5 (2011)