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Seminal plasma anti-müllerian hormone: a potential AI-boar fertility biomarker?

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dc.contributor.authorBarranco Cascales, Isabel
dc.contributor.authorFernández Fuertes, Beatriz
dc.contributor.authorPadilla, Lorena
dc.contributor.authorDelgado-Bermúdez, Ariadna
dc.contributor.authorTvarijonaviciute, Asta
dc.contributor.authorYeste, Marc
dc.contributor.departmentMedicina y Cirugía Animal
dc.contributor.otherFacultad de Veterinaria
dc.date.accessioned2025-10-17T10:25:38Z
dc.date.available2025-10-17T10:25:38Z
dc.date.copyright©2020 by the authors
dc.date.issued2020-04-10
dc.description.abstractThe anti-Müllerian hormone (AMH), a Sertoli cell-secreted glycoprotein that is present in seminal plasma (SP), is considered as a marker of spermatogenesis in humans. This study aimed to evaluate the presence of this hormone in boar SP, together with its putative relationship with sperm quality, function, and in vivo fertility parameters in liquid-stored semen samples. The concentration of SP-AMH was assessed in 126 ejaculates from artificial insemination (AI)-boars (n = 92) while using a commercial Enzyme-Linked ImmunoSorbent Assay (ELISA) kit with monoclonal antibodies specific for Sus scrofa AMH (CEA228Po, Cloud-clone). Sperm quality (concentration, motility, viability, and acrosome damage) and functionality (membrane lipid disorder and intracellular H2O2 generation) were assessed in semen samples at 0 and 72 h of liquid-storage. In addition, fertility parameters from 3113 sows inseminated with the AI-boars were recorded in terms of farrowing rate, litter size, number of stillbirths per litter, and the duration of pregnancy over a 12-month period. The results revealed that the SP-AMH concentration varied widely among boar ejaculates, with no differences among breeds. Moreover, the SP-AMH concentration proved to be a good predictive biomarker for sperm concentration (p ˂ 0.05), but poor for other sperm quality, functionality, and in vivo fertility parameters of liquid-stored semen samples from AI-boars.
dc.formatapplication/pdf
dc.format.extent13
dc.identifier.citation Biology 2020, 9, 78
dc.identifier.doihttps://doi.org/10.3390/biology9040078
dc.identifier.eissn2079-7737
dc.identifier.urihttp://hdl.handle.net/10201/167312
dc.languageeng
dc.publisherMDPI
dc.relationThis research was funded by European Commission (H2020-MSCA-IF-79212); Ministry of Science, Innovation and Universities, Spain (RYC-2014-15581, AGL2017-88329-R, FJCI-2017-31689 and PRE2018-083488); and Regional Government of Catalonia, Spain (2017-SGR-1229).The authors of this manuscript wish to thank AIM Iberica (Topigs Norsvin Iberica) for supplying the boar ejaculates
dc.relation.publisherversionhttps://www.mdpi.com/2079-7737/9/4/78
dc.rightsAttribution 4.0 Internacional
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectAnti-Müllerian hormone
dc.subjectArtificial insemination
dc.subjectFertility
dc.subjectInter-ejaculate variability
dc.subjectSeminal plasma
dc.subjectPorcine
dc.subjectSperm
dc.subject.odsNo relacionado con ningún objetivo de desarrollo sostenible
dc.titleSeminal plasma anti-müllerian hormone: a potential AI-boar fertility biomarker?
dc.typeinfo:eu-repo/semantics/article
dspace.entity.typePublicationes
relation.isAuthorOfPublication3c34d0d5-7d7d-4bcc-a119-8906f53baa7b
relation.isAuthorOfPublication51159b46-4514-4a54-9cc7-dea538fc1efa
relation.isAuthorOfPublication.latestForDiscovery3c34d0d5-7d7d-4bcc-a119-8906f53baa7b
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