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Ultrastructural computerized morphometry of platelets in chronic myelogenous leukemia making use of ultra-thin sections and freeze-fracture procedure a preliminary approach

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dc.contributor.authorBianciardi, G.es
dc.contributor.authorBattistelli, S.es
dc.contributor.authorToti, P.
dc.contributor.authorVallesi, G.
dc.contributor.authorWeber, G.
dc.date.accessioned2011-01-17T12:40:36Z
dc.date.available2011-01-17T12:40:36Z
dc.date.issued1988
dc.description.abstractBiochemical and morphological data have shown that the circulating platelets are deeply altered in patients with chronic mielogenous leukemia. In this report we describe the results of ultrastructural morphometry performed by means of a computerized device of the platelet shape (ultra-thin sectioned platelets) and of the platelet plasma-membrane (freezefractured platelets). Platelets appeared deeply modified: reduced mean platelet area and perimeter, increased surface density of the openings of the surface connected canalicular system, abnormal features of the platelet cytoplasm and some aspects of platelets joined together even if with heterogeneity in these findings did appear from patient to patient.
dc.formatapplication/pdfes
dc.format.extent5es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/17913
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectMorphometryes
dc.subjectLeukemiaes
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncologíaes
dc.titleUltrastructural computerized morphometry of platelets in chronic myelogenous leukemia making use of ultra-thin sections and freeze-fracture procedure a preliminary approaches
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol. 3, nº 1 (1988)