Publication:
MicroRNAs: a critical regulator under mechanical force

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dc.contributor.authorWei, Fulan
dc.contributor.authorYang, Shuangyan
dc.contributor.authorWang, Songlin
dc.date.accessioned2022-04-06T07:41:46Z
dc.date.available2022-04-06T07:41:46Z
dc.date.issued2018
dc.description.abstractMechanical force is a kind of mechanical stimuli which actively participates in manipulating cellular activities in numerous types of cells. Progress in molecular and genetic research has uncovered various regulatory mechanisms underlying mechanical forceinduced changes in cellular activities, which include both transcriptional regulation and post-transcriptional regulation. MicroRNAs (miRNAs) are 20-25 nucleotide (nt) non-coding RNAs which serve as posttranscriptional regulators of multiple physiological processes. To date, considerable research effort has focused on the expressions and functions of miRNAs in a wide range of biological and pathological processes, including but not limited to development, proliferation, metabolism and osteogenic differentiation. In this review, major emphasis is placed on the biogenesis, expressions and functions of miRNAs in a mechanical environment.es
dc.formatapplication/pdfes
dc.format.extent8es
dc.identifier.citationHistology and Histopathology, Vol.33, nÂş4, (2018)
dc.identifier.doiDOI: 10.14670/HH-11-924
dc.identifier.issn1699-5848
dc.identifier.issn0213-3911
dc.identifier.urihttp://hdl.handle.net/10201/118785
dc.languageenges
dc.publisherUniversidad de Murcia. Departamento de BiologĂ­a Celular e HistologĂ­aes
dc.relationSin financiaciĂłn externa a la Universidades
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectMicroRNAses
dc.subjectMechanical Forcees
dc.subjectPosttranscriptional regulatores
dc.subjectOsteogenic differentiationes
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::616 - PatologĂ­a. Medicina clĂ­nica. OncologĂ­aes
dc.titleMicroRNAs: a critical regulator under mechanical forcees
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.33, nÂş4 (2018)