Publication:
Observations on cell kinetics and viability of a human melanoma cell line exposed to dicarboxylic acids in tissue culture

dc.contributor.authorBreathnach, A. S.es
dc.contributor.authorRobins, E.J.es
dc.contributor.authorBhasin, Y. P.
dc.contributor.authorEthridge, L. B.
dc.contributor.authorNazzaro-Porro, M.
dc.contributor.authorPassi, S.
dc.contributor.authorPicardo, M.
dc.date.accessioned2011-01-17T12:39:17Z
dc.date.available2011-01-17T12:39:17Z
dc.date.issued1986
dc.description.abstractCultures of human nlelanonla cell line BOO08 \verc e-iposed to the disodium salts of arelaic acid (C,, 2Na), adipic acid (C,, 2Na) and dodecanediaic acid (C,, 2Na) at IO'M and 5 x 10-'M for 24 hrs. None of the diacid salts had a significant effect on growth rate or viability of the cells, at 10-'M for 24 hrs nor had C, 2Na any effect at 5 x 10'M. At 5 x 102M for 24 hrs, both C,, 2Na, and CIL2 Na had a significant effect in reducing both growth and viability. These effects were accompanied by morphological evidence of cell death, and swelling of mitochondria and accuni~~latioonf lipid droplets within cytoplasm of still biable cells.
dc.formatapplication/pdfes
dc.format.extent5es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/17825
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectMelanomaes
dc.subjectDicarboxylic acidses
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología::616.5 - Piel. Dermatología clínicaes
dc.titleObservations on cell kinetics and viability of a human melanoma cell line exposed to dicarboxylic acids in tissue culturees
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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