Publication: Hair regeneration using adipose-derived stem cells
Authors
Jin, Su-Eon ; Sung, Jong-Hyuk
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Publisher
Universidad de Murcia. Departamento de BiologĂa Celular e HistologĂa
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DOI
10.14670/HH-11-686
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info:eu-repo/semantics/article
Description
Abstract
Adipose-derived stem cells (ASCs) have
been used in tissue repair and regeneration. Recently, it
was reported that ASC transplantation promotes hair
growth in animal experiments, and a conditioned
medium of ASCs (ASC-CM) induced the proliferation
of hair-compositing cells in vitro. However, ASCs and
their conditioned medium have shown limited
effectiveness in clinical settings. ASC preconditioning is
one strategy that can be used to enhance the efficacy of
ASCs and ASC-CM. Therefore, we highlighted the
functional role of ASCs in hair cycle progression and
also the advantages and disadvantages of their
application in hair regeneration. In addition, we
introduced novel ASC preconditioning methods to
enhance hair regeneration using ASC stimulators, such
as vitamin C, platelet-derived growth factor, hypoxia,
and ultraviolet B.
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Citation
Histology and Histopathology, vol.31, nÂş3, (2016)
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Este Ătem está sujeto a una licencia Creative Commons. http://creativecommons.org/licenses/by-nc-nd/4.0/