Publication:
On the antitumor properties of novel cyclometalated benzimidazole Ru(II), Ir(III) and Rh(III) complexes

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ChemCommun_2013_RuRhIr_benzimidazole.pdf(403.93 KB)
Date
2013-10-17
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Authors
Yellol, Gorakh S. ; Donaire González, Antonio ; Yellol, Jyoti G. ; Vasylyeva, Vera ; Janiak, Christoph ; Ruiz, José
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Publisher
Royal Society of Chemistry
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publication.page.department
Química Inorgánica
DOI
DOI: 10.1039/c3cc46239k
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info:eu-repo/semantics/article
Description
Abstract
Smart design and efficient synthesis of benzimidazole Ru, Ir and Rh cyclometalated complexes are reported with promising cytotoxic activity against HT29, T47D, A2780 and A2780cisR cancer cell lines. Their apoptosis, accumulation, cell cycle arrest, protein binding and DNA binding effects are also discussed.
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anticancer compounds , ruthenium , iridium , rhodium , benzimidazole complexes , metal ion complexes
Citation
Chemical Communications,, 49, 2013, 11533.
URI
http://hdl.handle.net/10201/101953
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