Publication: Histopathology, pathogenesis and molecular genetics in primary central nervous system lymphomas
Authors
Nakamura, M. ; Shimada, K. ; Ishida, E. ; Konishi, N.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
Recent increases in the incidence of primary
central nervous system lymphoma (PCNSL), a rare non-
Hodgkin’s lymphoma arising in the brain, have been
noted in both immunodeficient and immunocompetent
patients. Compared with lymphomas originating outside
the central nervous system, the biology of PCNSL at the
molecular or cytogenetic level has not been well
characterized, yet it is important to thoroughly
understand the etiology of this rare malignant lymphoma
if effective therapies are to be developed. This review
will focus on the epidemiology, clinical aspects,
histopathology, pathogenesis, and molecular genetics of
this aggressive, extranodal lymphoma in
immunocompetent patients.
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Citation
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