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Magnesium in Kidney Function and Disease—Implications for Aging and Sex—A Narrative Review

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dc.contributor.authorMacías Ruiz, María del Carmen
dc.contributor.authorCuenca, Lorena
dc.contributor.authorVeronese, Nicola
dc.contributor.authorFernández Villalba, Emiliano
dc.contributor.authorKublickiene, Karolina
dc.contributor.authorRaparelli, Valeria
dc.contributor.authorNorris, Colleen M.
dc.contributor.authorKautzky-Willer, Alexandra
dc.contributor.authorPilote, Louise
dc.contributor.authorBarbagallo, Mario
dc.contributor.authorDominguez, Ligia
dc.contributor.authorGonzález Cuello, Ana María
dc.contributor.authorHerrero Ezquerro, María Trinidad
dc.contributor.departmentEnfermería
dc.date.accessioned2024-02-09T09:25:12Z
dc.date.available2024-02-09T09:25:12Z
dc.date.issued2023-03
dc.description©2023. This manuscript version is made available under the CC-BY 4.0 license http://creativecommons.org/licenses/by /4.0/ This document is the Published version of a Published Work that appeared in final form in Nutrients. To access the final edited and published work see https://doi.org/ 10.3390/nu15071710
dc.description.abstractMagnesium (Mg) has a vital role in the human body, and the kidney is a key organ in the metabolism and excretion of this cation. The objective of this work is to compile the available evidence regarding the role that Mg plays in health and disease, with a special focus on the elderly population with chronic kidney disease (CKD) and the eventual sex differences. A narrative review was carried out by executing an exhaustive search in the PubMed, Scopus, and Cochrane databases. Ten studies were found in which the role of Mg and sex was evaluated in elderly patients with CKD in the last 10 years (2012–2022). The progression of CKD leads to alterations in mineral metabolism, which worsen as the disease progresses. Mg can be used as a coadjuvant in the treatment of CKD patients to improve glomerular filtration, but its use in clinical applications needs to be further characterized. In conclusion, there’s a need for well-designed prospective clinical trials to advise and standardize Mg supplementation in daily clinical practice, taking age and sex into consideration.es
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dc.format.extent14es
dc.identifier.citationNutrients
dc.identifier.doihttps://doi.org/ 10.3390/nu15071710
dc.identifier.issn2072-6643
dc.identifier.urihttp://hdl.handle.net/10201/139031
dc.languageenges
dc.relationThe GOING-FWD Consortium was funded by the GENDER-NET Plus ERA-NET Initiative [Project Ref. no.: GNP-78]: “La Caixa” Foundation [ID 100010434] with code LCF/PR/DE18/52010001, Canadian Institutes of Health Research [GNP-161904], Swedish Research Council [2018-00932], Austrian Science Fund [FWF, I 4209]; MTH is funded by UM and in addition funded by UM/R714/2021. Open Access Funding by the Austrian Science Fund (FWF). All authors have read and agreed to the published version of the manuscript.es
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rightsAtribución 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectAginges
dc.subjectElderlyes
dc.subjectChronic kidney diseasees
dc.subjectSex differenceses
dc.titleMagnesium in Kidney Function and Disease—Implications for Aging and Sex—A Narrative Reviewes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
relation.isAuthorOfPublication9bbe7af5-429b-4029-b621-0399a6838322
relation.isAuthorOfPublication.latestForDiscovery9bbe7af5-429b-4029-b621-0399a6838322
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