Subpallial origin of part of the calbindin-positive neurons of the claustral complex and piriform cortex

García López, Margarita; Medina, Loreta; Legaz Pérez, Isabel

Publication:
Subpallial origin of part of the calbindin-positive neurons of the claustral complex and piriform cortex

dc.contributor.author	García López, Margarita
dc.contributor.author	Medina, Loreta
dc.contributor.author	Legaz Pérez, Isabel
dc.contributor.department	Ciencias Sociosanitarias
dc.date.accessioned	2024-07-12T08:50:55Z
dc.date.available	2024-07-12T08:50:55Z
dc.date.copyright	© 2005 Elsevier Inc.
dc.date.issued	2005-09-15
dc.description.abstract	The aim of the present study was to investigate whether part of the calbindin-positive neurons of the claustral complex and piriform cortex originate in the subpallium. To that end, we prepared organotypic cultures of embryonic telencephalic slices, and applied the cell tracker CMTMR to the ventricular/subventricular zone of the lateral or medial ganglionic eminence. Following 48 h of incubation, we observed a number of CMTMR-labeled cells (showing red fluorescence) of subpallial origin in the claustral complex and piriform cortex. To know whether some of these cells of subpallial origin were calbindin-positive, we performed immunofluorescence for calbindin using an Alexa 488-conjugated secondary antiserum (green fluorescence). Our results showed that some of the CMTMR-labeled cells of subpallial origin in the claustral complex and piriform cortex are calbindin-positive (and possibly GABAergic). The subpallial origin of part of these cells was confirmed by observation of double labeled neurons in the claustral complex that expressed both Lhx6 mRNA (a marker of cells derived from the medial ganglionic eminence) and calbindin. Future studies will be required to analyze the existence of a subpopulation of non-GABAergic calbindin cells in the claustral complex and piriform cortex, and to know their origin.	es
dc.format	application/pdf	es
dc.format.extent	5	es
dc.identifier.citation	Brain Research Bulletin, 2005, Vol. 66, Issues 4–6, pp. 470-474
dc.identifier.doi	https://doi.org/10.1016/j.brainresbull.2005.05.006
dc.identifier.issn	Print: 0361-9230
dc.identifier.uri	http://hdl.handle.net/10201/143060
dc.language	eng	es
dc.publisher	Elsevier
dc.relation	This work was supported by the Spanish Ministry of Science and Technology (CYCIT-FEDER; grants BFI2000-1359-C02-02 and BFI2003-06453-C02-02 to L.M.; fellowship FP2000-5943 to I.L.), the Spanish Ministry of Health-Institute Carlos III (FIS-FEDER grant 01/0057-02 to L.M. and Red CIEN-Nodo 318) and Séneca Foundation (grant PB/50/FS/02 to L.M.).	es
dc.relation.publisherversion	https://www.sciencedirect.com/science/article/pii/S0361923005001693#aep-acknowledgment-id20
dc.rights	Attribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.accessRights	info:eu-repo/semantics/openAccess
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject	Interneurons	es
dc.subject	Claustrum	es
dc.subject	Endopiriform nucleus	es
dc.subject	Tangential migration	es
dc.subject	Lhx6	es
dc.title	Subpallial origin of part of the calbindin-positive neurons of the claustral complex and piriform cortex	es
dc.type	info:eu-repo/semantics/article	es
dc.type.version	info:eu-repo/semantics/publishedVersion
dspace.entity.type	Publication	es
relation.isAuthorOfPublication	b83b4b59-2d61-40f0-9108-5c6a6d158295
relation.isAuthorOfPublication.latestForDiscovery	b83b4b59-2d61-40f0-9108-5c6a6d158295