Acoustic radiation force impulse imaging for evaluation of the thyroid gland

Cepero Calvete, Ángela; Berná Mestre, Juan de Dios; Rodriguez Gonzalez, José Manuel; Sáez Martinez, Elena; Torregrosa Sala, Begoña; Rios Zambudio, Antonio

Publication:
Acoustic radiation force impulse imaging for evaluation of the thyroid gland

dc.contributor.author	Cepero Calvete, Ángela
dc.contributor.author	Berná Mestre, Juan de Dios
dc.contributor.author	Rodriguez Gonzalez, José Manuel
dc.contributor.author	Sáez Martinez, Elena
dc.contributor.author	Torregrosa Sala, Begoña
dc.contributor.author	Rios Zambudio, Antonio
dc.contributor.department	Dermatología, Estomatología, Radiología y Medicina Física
dc.date.accessioned	2025-01-17T09:36:04Z
dc.date.available	2025-01-17T09:36:04Z
dc.date.issued	2014-06-01
dc.description	© 2014 by the American Institute of Ultrasound in Medicine. This document is the Published Manuscript version of a Published Work that appeared in final form in Journal of Ultrasound in Medicine. To access the final edited and published work see https://doi.org/10.7863/ultra.33.6.1031
dc.description.abstract	To study acoustic radiation force impulse (ARFI) imaging as a new quantitative and noninvasive tool for evaluating thyroid nodules and to compare ARFI imaging with other tools for studying thyroid nodules: sonography, real-time elastography, and fine-needle aspiration biopsy. We conducted a prospective study from June 2011 to June 2012, which analyzed 157 thyroid nodules (129 benign and 28 malignant) using the ARFI technique and a 9-MHz probe. Shear wave velocities (SWVs) were obtained while the patients held their breath to avoid respiratory movement artifacts. All nodules underwent conventional sonography and real-time elastography of the thyroid gland. All patients received either a cytologic examination using fine-needle aspiration biopsy or a histologic examination from thyroid surgery to verify the diagnosis (reference standard). The mean SWV ± SD on ARFI imaging in healthy, nodule-free thyroid glands was 2.04 ± 0.51 m/s (range, 0.76–3.63 m/s). The mean SWV in benign thyroid nodules was 1.70 ± 0.55 m/s (range, 0.50–2.80 m/s), and the mean SWV in malignant nodules was 3.39 ± 1.15 m/s (range, 1.50–6.08 m/s). When we used an SWV greater than 2.50 m/s for the diagnosis of malignant nodules and less than 2.50 m/s for the diagnosis of benign nodules, the sensitivity and specificity of ARFI imaging were 85.7% and 96.0%, respectively. We found that SWVs were substantially higher in malignant nodules than benign ones. Perhaps if ARFI imaging is used in conjunction with sonographic findings and patient demographics, it will be possible to find a combination of factors that would yield a negative predictive value high enough to distinguish benign from malignant nodules with confidence, which may lead to a decrease in the biopsy rate for benign nodules.	es
dc.format	application/pdf	es
dc.format.extent	10	es
dc.identifier.citation	Journal of Ultrasound in Medicine, 2014, Vol. 66, Issue 6, pp. 1031-1040
dc.identifier.doi	https://doi.org/10.7863/ultra.33.6.1031
dc.identifier.issn	Print: 0278-4297
dc.identifier.issn	Electronic: 1550-9613
dc.identifier.uri	http://hdl.handle.net/10201/148647
dc.language	eng	es
dc.publisher	Wiley	es
dc.relation	Sin financiación externa a la Universidad	es
dc.relation.publisherversion	https://onlinelibrary.wiley.com/doi/10.7863/ultra.33.6.1031
dc.rights.accessRights	info:eu-repo/semantics/restrictedAccess
dc.subject	Thyroid cancer	es
dc.subject	Thyroid	es
dc.subject	Ecografía	es
dc.subject.other	CDU::6 - Ciencias aplicadas::61 - Medicina::615 - Farmacología. Terapéutica. Toxicología. Radiología	es
dc.title	Acoustic radiation force impulse imaging for evaluation of the thyroid gland	es
dc.type	info:eu-repo/semantics/article	es
dspace.entity.type	Publication	es