Publication: Comparative View on the Oviductal Environment during the Periconception Period.
Authors
González-Brusi, Leopoldo ; Algarra, Blanca ; Izquierdo Rico, María José ; Avilés Sánchez, Manuel ; Jíménez Movilla, María ; Moros Nicolás, Carla
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Publisher
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DOI
10.3390/biom10121690
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info:eu-repo/semantics/article
Description
©2020. This manuscript version is made available under the CC-BY 4.0 license http://creativecommons.org/licenses/by /4.0/
This document is the Published, version of a Published Work that appeared in final form in Biomolecules. To access the final edited and published work see https://doi.org/10.3390/biom10121690
Abstract
The oviduct plays important roles in reproductive events: sperm reservoir formation,
final gamete maturation, fertilization and early embryo development. It is well known that the
oviductal environment affects gametes and embryos and, ultimately, the health of offspring, so that
in vivo embryos are better in terms of morphology, cryotolerance, pregnancy rates or epigenetic
profile than those obtained in vitro. The deciphering of embryo–maternal interaction in the oviduct
may provide a better understanding of the embryo needs during the periconception period to improve
reproductive efficiency. Here, we perform a comparative analysis among species of oviductal gene
expression related to embryonic development during its journey through the oviduct, as described
to date. Cross-talk communication between the oviduct environment and embryo will be studied
by analyses of the secreted or exosomal proteins of the oviduct and the presence of receptors in the
membrane of the embryo blastomeres. Finally, we review the data that are available to date on the
expression and characterization of the most abundant protein in the oviduct, oviductin (OVGP1),
highlighting its fundamental role in fertilization and embryonic development.
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Biomolecules
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