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An adverse effect of Ocrelizumab treatment in a patient with multiple sclerosis: a case report of necrotizing periodontitis

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dc.contributor.authorMontoya Carralero, José María
dc.contributor.authorSánchez Pérez, Arturo Joaquín
dc.contributor.authorJornet García, Alfonso Felipe
dc.contributor.authorMoya Villaescusa, María José
dc.contributor.departmentDermatología, Estomatología, Radiología y Medicina Física
dc.date.accessioned2024-09-04T08:25:16Z
dc.date.available2024-09-04T08:25:16Z
dc.date.copyright© 2023 by the Authors & Gavin Publishers
dc.date.issued2023-04-04
dc.description.abstractMultiple Sclerosis (MS) and Necrotizing Periodontitis (NP) are two diseases whose aetiologies and pathophysiologies do not appear to have a common link; however, treating MS with monoclonal antibodies and the decrease in humoral immunity that this entails can be a trigger or an aggravation in patients who present with quiescent NP. We describe a clinical case of NP, including clinical manifestations, treatment, and evolution during therapy with ocrelizumab and to review risk factors. A rapid progression of NP was evidenced. During the patient’s evolution, she suffered bilateral pneumonia due to coronavirus disease 2019, requiring treatment with corticosteroids and antibiotics, which led to clinical relief of her NP. Based on this case, we believe that regulated dental monitoring of patients with MS before, during, and after the administration of monoclonal antibodies may help prevent periodontal deterioration.es
dc.formatapplication/pdfes
dc.format.extent6es
dc.identifier.citationDentistry: Advanced Research, 2023, Vol.7 , N. 2: 203
dc.identifier.doihttps://doi.org/10.29011/2574-7347.100103
dc.identifier.issnElectronic: 2574-7347
dc.identifier.urihttp://hdl.handle.net/10201/143559
dc.languageenges
dc.publisherGavin Publishers
dc.relationSin financiación externa a la Universidad.es
dc.relation.publisherversionhttps://www.gavinpublishers.com/article/view/an-adverse-effect-of-ocrelizumab-treatment-in-a--patient-with-multiple-sclerosis-a-case-report-of-necrotizing-periodontitis
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rightsAtribución-CompartirIgual 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-sa/4.0/*
dc.subjectMultiple sclerosises
dc.subjectNecrotizing periodontitises
dc.subjectPeriodontal diseasees
dc.subjectPeriodontal treatmentes
dc.subjectPeriodontitises
dc.subjectRelapsing remitting multiple sclerosises
dc.titleAn adverse effect of Ocrelizumab treatment in a patient with multiple sclerosis: a case report of necrotizing periodontitises
dc.typeinfo:eu-repo/semantics/articlees
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dspace.entity.typePublicationes
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relation.isAuthorOfPublication.latestForDiscoverya55c0b7c-757c-4ab6-a37c-9108adcfd1ef
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