Publication: Effects of photo stimulation and nonstimulation of golden hamsters (Mesocricetus auratus) from birth to early puberty on testes structure and function
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Date
2009
Authors
Hance, Michael W. ; Mason, J.Ian ; Chamindrani Mendis-Handagama, S.M.L.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
We tested whether puberty in golden
hamsters is photoperiodically controlled. Hamsters were
raised under 14:10 hours Light:Dark (14L) and 1:23
hours Light:Dark (1L) respectively, from birth to 28
days and tested for various parameters. Body weight,
Leydig cell (LC) size and testicular testosterone
secretion were greater and plasma thyroxin (T4),
testicular androstenedione secretion and LC number
were lower (P<0.05) in 1L than 14L hamsters. Volumes
of testicular components were similar in the two groups.
3ß-hydroxy steroid dehydrogenase immunohistochemistry
demonstrated LC progenitors and newly
formed adult LC (ALC) in 14L hamsters, which were
absent in 1L hamsters; they contained only fetal LC
(FLC). Latter findings suggest the presence and absence
of postnatally-differerentiated LC in 14L and 1L
hamsters, respectively. Androgen results agreed with
these findings, because FLC primarily secrete
testosterone, and androstenedione is a major androgen
secreted by the newly formed ALC. Reduced T4 in 1L
hamsters is attributed to the inhibition of thyroid
function by the increased duration of melatonin secretion
due to non-photostimulatory conditions. The arrest in LC
differentiation in 1L hamsters is attributed to low T4
levels. Although the testis size is unaltered under nonphotostimulatory
conditions, postnatal LC differentiation
is inhibited in golden hamsters, and therefore, it is
logical to suggest that their puberty is photoperiodically
controlled.
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