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Stability and predictors of poor 6-min walking test performance over 2 years in patients with COPD

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dc.contributor.authorSánchez Martínez, Mª Piedad
dc.contributor.authorBernabeu Mora, Roberto
dc.contributor.authorMartínez González, Mariano
dc.contributor.authorGacto Sánchez, Mariano Luis
dc.contributor.authorMartín San Agustín, Rodrigo
dc.contributor.authorMedina i Mirapeix, Francesc
dc.contributor.departmentFisioterapia
dc.contributor.otherFacultad de Medicina
dc.date.accessioned2024-02-08T13:02:57Z
dc.date.available2024-02-08T13:02:57Z
dc.date.copyright© 2020 by the authors
dc.date.issued2020-04-18
dc.description.abstractPoor performance in the 6-min walk test (6MWT < 350 m) is an important prognostic indicator of mortality and risk of exacerbations in patients with chronic obstructive pulmonary disease (COPD). Little is known about the stability of this state over time and what factors might predict a poor 6MWT performance. To determine the stability of 6MWT performance over a 2-year period in COPD patients participating in annual medical follow-up visits, and to assess the ability of several clinical, pulmonary, and non-pulmonary factors to predict poor 6MWT performance, we prospectively included 137 patients with stable COPD (mean age, 66.9 8.3 years). The 6MWT was scored at baseline and 2-year follow-up. To evaluate clinical, pulmonary, and non-pulmonary variables as potential predictors of poor 6MWT performance, we used multiple logistic regression models adjusted for age, sex, weight, height, and 6MWT performance at baseline. Poor 6MWT performance was stable over 2 years for 67.4% of patients. Predictors of poor 6MWT performance included a five-repetition sit-to-stand test score 2 (OR, 3.01; 95% CI, 1.22–7.42), the percentage of mobility activities with limitations (OR, 1.03; 95% CI, 1.00–1.07), and poor 6MWT performance at baseline (OR, 4.64; 95% CI, 1.88–11.43). Poor 6MWT performance status was stable for the majority of COPD patients. Lower scores on the five-repetition sit-to-stand test and a higher number of mobility activities with limitations were relevant predictors of poor 6MWT performance over 2 years. Prognostic models based on these non-pulmonary factors can provide non-inferior discriminative ability in comparison with prognostic models based on only pulmonary factors.es
dc.formatapplication/pdfes
dc.format.extent12es
dc.identifier.citationJournal of Clinical Medicine, 9, 2020: 1155
dc.identifier.doihttps://doi.org/10.3390/jcm9041155
dc.identifier.eissn2077-0383
dc.identifier.urihttp://hdl.handle.net/10201/139016
dc.languageenges
dc.publisherMDPIes
dc.relation The study was supported by AstraZenecaes
dc.relation.publisherversionhttps://www.mdpi.com/2077-0383/9/4/1155
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rightsAttribution 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subject6MWTes
dc.subjectCOPDes
dc.subjectPredictorses
dc.subject5STSes
dc.subjectMobility activitieses
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncologíaes
dc.titleStability and predictors of poor 6-min walking test performance over 2 years in patients with COPDes
dc.typeinfo:eu-repo/semantics/articlees
dc.type.versioninfo:eu-repo/semantics/publishedVersión
dspace.entity.typePublicationes
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