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Ellagic acid–borax fluorescence interaction: application for novel cyclodextrin-borax nanosensors for analyzing ellagic acid in food samples

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dc.contributor.authorMatencio Durán, Adrián
dc.contributor.authorNavarro Orcajada, Silvia
dc.contributor.authorLópez Nicolás, José Manuel
dc.contributor.authorGarcía Carmona, Francisco
dc.contributor.departmentBioquímica y Biología Molecular A
dc.contributor.otherFacultad de Biología
dc.date.accessioned2026-02-24T11:59:58Z
dc.date.available2026-02-24T11:59:58Z
dc.date.copyright© 2018, The Royal Society of Chemistry
dc.date.issued2018-06-18
dc.description.abstractThe food industry needs cheap, fast and sensitive methods to increase the number of analyses that are routinely carried out; for this reason, new methods are constantly being sought. This paper describes a novel fluorescent nanosensor based on cyclodextrin (CD) to determine ellagic acid (EA). The encapsulation of EA in the presence of borax was studied. Firstly, the complexation of EA–borax was tested. The stoichiometry of the EA–borax complex showed a 1 : 2 complex, with KF1 = 2548 ± 127 M−1 and KF2 = 302 ± 15 M−1. Different CDs were used to obtain a 1 : 1 : 1 CD–EA–borax complex with γ-CD providing the best complexation constant (KF3 = 364 ± 18 M−1). Furthermore, when the accuracy and sensitivity of the nanosensor were tested using a crude blueberry extract, the CD/borax mixture provided an 18 times stronger signal than with the crude extract alone and 7 times stronger than that obtained using borax alone.
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dc.format.extent5
dc.identifier.citationFood Funct., 2018,9, 3683-3687
dc.identifier.doihttps://doi.org/10.1039/c8fo00906f
dc.identifier.eissn2042-650X
dc.identifier.issn2042-6496
dc.identifier.urihttp://hdl.handle.net/10201/212061
dc.languageeng
dc.publisherRoyal Society of Chemistry
dc.relationThis work was supported by “Ministerio de Economía, Industria y Competitividad” (MINECO, FSE, Spain) (Project AGL2014-57431-P and project AGL2017-86526-P) and by “Programa de ayudas a Grupos de Excelencia de la Región de Murcia, de la Fundación Séneca, Agencia de Ciencia y Tecnología de la Región de Murcia” No. 19893/GERM/2015. Adrián Matencio holds a contract “FPU UM” from the University of Murcia (R-1042/2015).
dc.relation.publisherversionhttps://pubs.rsc.org/en/content/articlelanding/2018/fo/c8fo00906f
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subject.odsNo relacionado con ningún objetivo de desarrollo sostenible
dc.titleEllagic acid–borax fluorescence interaction: application for novel cyclodextrin-borax nanosensors for analyzing ellagic acid in food samples
dc.typeinfo:eu-repo/semantics/article
dc.type.versioninfo:eu-repo/semantics/acceptedVersion
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