X-ray micro-computed tomography characterization of autologous teeth particle used in postextraction sites for bone regeneration. An experimental study in dogs

Calvo Guirado, José Luis; Carlos Villafranca, Félix de; Garcés Villalá, Miguel; García Carrillo, Nuria; Jindal, Vidushi; Martínez Martínez, Francisco

Publication:
X-ray micro-computed tomography characterization of autologous teeth particle used in postextraction sites for bone regeneration. An experimental study in dogs

dc.contributor.author	Calvo Guirado, José Luis
dc.contributor.author	Carlos Villafranca, Félix de
dc.contributor.author	Garcés Villalá, Miguel
dc.contributor.author	García Carrillo, Nuria
dc.contributor.author	Jindal, Vidushi
dc.contributor.author	Martínez Martínez, Francisco
dc.contributor.department	Cirugía, Pediatría y Obstetricia y Ginecología
dc.date.accessioned	2025-05-08T10:54:02Z
dc.date.available	2025-05-08T10:54:02Z
dc.date.issued	2022-04-26
dc.description	© 2022 Indian Journal of Dental Sciences. This manuscript version is made available under the CC-BY-NC-SA 4.0 license http://creativecommons.org/licenses/by-nc-sa/4.0/ This document is the Published Manuscript version of a Published Work that appeared in final form in Indian Journal of Dental Sciences. To access the final edited and published work see https://doi.org/10.4103/ijds.ijds_138_21
dc.description.abstract	Objectives: The objective of this study was to develop a new computed method to characterize and measure the bone density measured in Hounsfield units (HU) of particulate tooth grafts, evaluated by micro-computed tomography (micro-CT) at 2 months of healing. Materials and Methods: Thirty-two dog teeth were crushed with a smart dentin grinder, later implanted in postextraction sites of 4 beagle dogs. Twenty-four cores were taken after 2 months and analyzed by micro-CT (Albira). The methodology used was based on a descriptive statistic of the bone density values measured in HU obtained from the creation of volumes of interest (VOIs) and predefined three-dimensional iso-contours from the images obtained after performing micro-CT of the biopsies of the crushing tooth. Results: The micro-CT allows established the characteristics of the biomaterials by studying the HU. The most predominant type of bone was type D3 density (400–800 HU). There was a light presence of bone-type density D2 and D1 in 2 of the regions studied. Conclusions: Micro-CT could be considered a technique of great value in the characterization of biomaterials based on the HU, after implantation in an in vivo model. The distribution of D1 and D2 particles were located around the bottom and middle part of the alveoli and the D3 and D4 bone particles were in the hole core. Therefore, the method proposed in this study is useful to determine the density of the tooth granulate (dentin grinder) and any other biomaterial.	es
dc.format	application/pdf	es
dc.format.extent	10	es
dc.identifier.citation	Indian Journal of Dental Sciences, 2022, Vol. 14(2), pp 58-67
dc.identifier.doi	https://doi.org/10.4103/ijds.ijds_138_21
dc.identifier.issn	Print: 0976-4003
dc.identifier.issn	Electronic: 2231-2293
dc.identifier.uri	http://hdl.handle.net/10201/154286
dc.language	eng	es
dc.publisher	Wolters Kluwer
dc.relation	Sin financiación externa a la Universidad	es
dc.relation.publisherversion	https://journals.lww.com/ijds/fulltext/2022/14020/x_ray_micro_computed_tomography_characterization.2.aspx
dc.rights	info:eu-repo/semantics/openAccess	es
dc.rights	Atribución-NoComercial-CompartirIgual 4.0 Internacional	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-sa/4.0/	*
dc.subject	Bone density	es
dc.subject	Bone graft substitute	es
dc.subject	Autologous grafting	es
dc.subject	Dentin graft	es
dc.subject	Micro computed tomography	es
dc.title	X-ray micro-computed tomography characterization of autologous teeth particle used in postextraction sites for bone regeneration. An experimental study in dogs	es
dc.type	info:eu-repo/semantics/article	es
dspace.entity.type	Publication	es