Publication:
Alveolar cells in cyclophosphamide-induced lung injury. II. Pathogenesis of experimental endogenous lipid pneumonia

Simple item page
dc.contributor.authorSulkowski, S.es
dc.contributor.authorSulkowska, M.es
dc.date.accessioned2011-02-22T11:10:25Z
dc.date.available2011-02-22T11:10:25Z
dc.date.issued1999
dc.description.abstractAn ultrastructural and histological study was made to analyse the structural and cellular features of the pulmonary lesions produced in Wistar rats by intraperitoneal (i.p.) administration of cyclophosphamide (two i.p. doses of 150 mg CP/1 kg bwtl m1 PBS). Rats exposed to cyclophosphamide (CP) developed a condition whose morphological picture corresponded to endogenous lipid pneumonia andlor pulmonary alveolar proteinosis-like changes. Damage to the endothelium and neutrophil accumulation in lung vascular bed were found to be potential initiators of endogenous lipid pneumonia-type changes. The possibility of the evolution of the acute lung injury into endogenous lipid pneumonia-type changes and into alveolar proteinosislike changes was demonstrated. The results of the study supplement the existing theories of pulmonary alveolar proteinosis pathogenesis.es
dc.formatapplication/pdfes
dc.format.extent8es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/19259
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectLung damagees
dc.subjectCyclophosphamidees
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicinaes
dc.titleAlveolar cells in cyclophosphamide-induced lung injury. II. Pathogenesis of experimental endogenous lipid pneumoniaes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Alveolar cells in cyclophosphamideinduced lung injury. II. Pathogenesis of experimental endogenous lipid pneumonia.pdf
Size:
5.32 MB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Histology and histopathology Vol.14, nº 4 (1999)