Publication: Ovarian pluripotent/multipotent stem
cells and in vitro oogenesis in mammals
Authors
Virant-Klun, Irma ; Stimpfel, Martin ; Skutella, Thomas
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Publisher
Murcia: F. Hernández y J.F. Madrid, Universidad de Murcia, Departamento de Biología Celular e Histología
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DOI
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info:eu-repo/semantics/article
Description
Abstract
There has been a long persisting dilemma
about potential ovarian stem cells in adult mammalian
ovaries, including human, and now there is steadily
increasing experimental evidence on their existence.
After some previous indirect evidence about the
presence of stem cells in adult mouse ovaries, an
important breakthrough was made by Zou and his coworkers
who successfully established long-persisting
pluripotent/multipotent ovarian stem cell lines in
neonatal and adult mice, and were followed by some
other important studies in mouse and human. Moreover,
oocyte-like cells can be developed in vitro from
pluripotent stem cells of different origins (embryonic
stem cells, induced pluripotent stem cells, fetal skin stem
cells, pancreatic stem cells). The aim of this article is to
elucidate the fast growing new knowledge on the ovarian
stem cells and potential in vitro oogenesis in mammals.
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Citation
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