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Repositorio Institucional de la Universidad de Murcia

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Browsing by Subject "Suphomucins"

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    Metaplasia intestinal gástrica. Asociaciones clínico-patológicas e importancia de la secreción de sulfomucinas en un área de bajo riesgo de cáncer gástrico
    (Elsevier, 1991) Martínez Díaz, F.; Ortuño Pacheco, G.; Oftalmología, Optometría, Otorrinolaringología y Anatomía Patológica
    We studied the relationship between the types of entera/ metaplasia, the clinicopathologic parameters (sex, age, location and endoscopic findings) and other abnormalities such as atrophic gastritis, gastric dysplasia and gastric cancer in low risk geographic area. We analized 850 gastric specimens from the "S,. María del Rosell" Hospital and the Department of Pathology of the Medica/ school of Murcia. Our results showed a positive relationship between enteral metaplasia and age (>50 years), antral region, gastric ulcer, atrophic gastritis, gastric dysplasia and gastric adenocarcinoma of intestinal type. Entera/ metaplasia type 111 characterized by the secretion of sulphomucins, although more frequent in the intestinal type of carcinoma ( 3 l .25%) compared with benign lesions ( l 2. 5% ), has no value as screening test due to its low sensitivity (31.25%). However, its high specificity ( 100%) 􀁐uggests that it should be looked for in ali the cases o/intestinal metaplasia in order to select patients at high risk of gastric cancer. -------------------

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