Browsing by Subject "Shrinkage"

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    Assessment of murine brain tissue shrinkage caused by different histological fixatives using magnetic resonance and computed tomography imaging
    (F. Hernández y Juan F. Madrid. Universidad de Murcia: Departamento de Biología Celular e Histología, 2015) Wehrl, Hans F.; Bezrukov, Ilja; Wiehr, Stefan; Lehnhoff, Mareike; Fuchs, Kerstin; Mannheim, Julia G.; Quintanilla-Martine, Leticia; Kohlhofer, Ursula; Kneilling, Manfred; Pichler, Bernd J.; Sauter, Alexander W.
    Especially for neuroscience and the development of new biomarkers, a direct correlation between in vivo imaging and histology is essential. However, this comparison is hampered by deformation and shrinkage of tissue samples caused by fixation, dehydration and paraffin embedding. We used magnetic resonance (MR) imaging and computed tomography (CT) imaging to analyze the degree of shrinkage on murine brains for various fixatives. After in vivo imaging using 7 T MRI, animals were sacrificed and the brains were dissected and immediately placed in different fixatives, respectively: zinc-based fixative, neutral buffered formalin (NBF), paraformaldehyde (PFA), Bouin-Holland fixative and paraformaldehyde-lysine-periodate (PLP). The degree of shrinkage based on mouse brain volumes, radiodensity in Hounsfield units (HU), as well as non-linear deformations were obtained. The highest degree of shrinkage was observed for PLP (68.1%, P<0.001), followed by PFA (60.2%, P<0.001) and NBF (58.6%, P<0.001). The zinc-based fixative revealed a low shrinkage with only 33.5% (P<0.001). Compared to NBF, the zinc-based fixative shows a slightly higher degree of deformations, but is still more homogenous than PFA. Tissue shrinkage can be monitored non-invasively with CT and MR. Zinc-based fixative causes the smallest degree of brain shrinkage and only small deformations and is therefore recommended for in vivo ex vivo comparison studies.
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    Tiempos que encogen: Tiempo, precariedad y encogimiento en las prácticas artísticas contemporáneas
    (Murcia: Servicio de publicaciones de la Universidad de Murcia, 2018) Labad Arias, Marta
    El propósito de este ensayo es traer al frente la dimensión temporal del trabajo creativo precario en el capitalismo posfordista. Para ello propondremos articular las nociones de tiempo, precariedad y encogimiento a partir de una serie de prácticas artísticas contemporáneas. Empezaremos por el encogimiento del tiempo privado que sufre el trabajador posfordista, desde Nosedive (Black Mirror) a la película In Time, para descubrir a continuación los encogimientos afectivos que provocan las inercias posfordistas en el ensayo visual titulado Dancismo (de Paz Rojo con Emilio Tomé), o en las perfomances, Paralysis y Largo (de Karel van Laere). Articularemos el encogimiento físico que sufren los protagonistas de The Shrinking Man o Downsizing con la vulnerabilidad a la que deben hacer frente los trabajadores precarios contemporáneos y acabaremos proponiendo un modo alternativo de recuperar el control sobre el tiempo a través de The Procrastinators