Browsing by Subject "Selenium"

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    Can inorganic elements affect herpesvirus infections in European eels?
    (Springer, 2019-11-14) Muñoz, Pilar; Barcala, Elena; Peñalver, José; Romero García, Diego; Sanidad Animal
    In combination, pollution and pathogens represent a serious threat to the health of European eels that has been increasingly recognized. Thus, the impact of contaminants, cadmium, lead, mercury, and selenium, on anguillid herpesvirus 1 infection in wild European eels has been evaluated. Despite the small sample size, results indicate that selenium and mercury concentrations may compromise the European eel immune system as herpesvirus infection was more prevalent in specimens with higher Hg and Se hepatic concentrations.
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    European eels and heavy metals from the Mar Menor lagoon (SE Spain)
    (Elsevier, 2020-06-20) Romero García, Diego; Barcala, Elena; Maria Dolores, Emilio; Muñoz, Pilar; Sanidad Animal
    Heavy metal pollution is related to the fall in European eel (Anguilla anguilla) populations. The Mar Menor lagoon (SE Spain) is home to an endangered population of this species, which is still caught for human consumption. The presence of Pb, Cd and Hg in the livers and muscles and the Se:Hg ratio in muscle of 150 eels from this lagoon were determined. Pb concentrations were higher than those reported from other populations in the world, while Cd and Hg concentrations in the tissues analysed were lower. In terms of food safety, Se concentrations play an important role in sequestering Hg in eels from this lagoon.
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    Roles of selenoprotein antioxidant protection in zebrafish, Danio rerio, subjected to dietary oxidative stress
    (Springer, 2015-03-07) Betancor, M B; Almaida Pagán, Pedro Francisco; Spreague, M; Hernandez, A; Tocher, D R; Fisiología
    In vertebrates, selenium (Se) is an essential micronutrient for vertebrates that is involved in antioxidant protection and thyroid hormone regulation among other roles and functions through its incorporation into proteins, the selenoproteins. Long-chain polyunsaturated fatty acids, such as docosahexaenoic acid (DHA), are essential nutrients for fish although high dietary levels may lead to increased oxidative stress due to the high degree of unsaturation. The present study investigated the effects of Se supplementation on zebrafish, Danio rerio, oxidative status together with selenoprotein expression profiles when subjected to a high-DHA diet. Fish were fed for 8 weeks with one of the four experimental diets, containing high or low-DHA in combination with or without organic Se (7 mg/kg). Fish performance, Se content, fatty acid composition and TBARS of zebrafish were determined, as well as gene expression of selected selenoproteins in liver and muscle. The Se levels in whole fish reflected dietary content. High dietary DHA increased oxidative stress as indicated by reduced growth and high TBARS content, although Se supplementation reduced oxidation. The expression patterns of selenoproteins varied between liver and muscle with only deiodinase type II displaying a transcriptional response when high dietary Se was supplied. High dietary DHA decreased selenoprotein expression in muscle and sps2 expression in liver regardless of the dietary Se content. These data suggest that oxidative stress protection associated with a high dietary intake of Se may not be solely mediated by transcriptional changes in teleost selenoprotein expression.
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    Tissue Distribution of Mercury and Its Relationship with Selenium in Atlantic Bluefin Tuna (Thunnus thynnus L.)
    (MDPI, ) Belmonte, Antonio; Muñoz, Pilar; Santos Echeandía, Juan; Romero García, Diego; Sanidad Animal; Ciencias Sociosanitarias