Browsing by Subject "Photobiomodulation"

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    Effect of Photobiomodulation on Atrophic–Erosive Clinical Forms of Oral Lichen Planus: A Systematic Review
    (MDPI, 2022-11-27) Ruiz Roca, Juan Antonio; López Jornet, María Pía; Gómez García, Francisco José; Marcos Aroca, Paula; Dermatología, Estomatología, Radiología y Medicina Física
    Abstract: Introduction. Oral lichen planus is a chronic autoimmune inflammatory disease of unknown origin, characterized by various clinical forms of which the atrophic–erosive causes patients the greatest symptomatology. For this reason, there are different treatments that improve the associated signs and symptoms. One of these therapies is photobiomodulation (PBM), which, although new, has a high level of acceptance in dentistry based on evidence. However, there are inconsistent results in its application against lichen planus. The aim of this review was to evaluate the effect of photobiomodulation and its effectiveness as a therapeutic alternative for atrophic–erosive lesions. Material and methods. The databases PubMed, Google Scholar and Cochrane Library were searched to identify studies investigating the photobiomodulation treatment in atrophic–erosive lesions of oral lichen planus. A total of 294 articles were identified, published between 2017 and 2022, and then evaluated; 7 articles that met all the inclusion criteria were included in this study. Results. The type of laser light source used in PBM was the diode laser (four cases), the Nd–YAG laser at the same wavelength of 1064 nm (two cases) and the He–Ne laser (one case). The minimum and maximum wavelengths used were 630 nm and 1064 nm, respectively. Most studies used lesions treated with topical corticosteroids as a control group. The follow-up times of the studies were highly variable. Conclusions. Photobiomodulation is a treatment that competently combats oral lichen planus lesions by improving signs and symptoms, with no known adverse reactions so far, which makes it more beneficial compared to more conventional therapies, such as corticosteroids, for which side effects have been found.
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    La fotobiomodulación puede aumentar la tolerancia al ejercicio y la activación de los músculos del antebrazo en hombres sanos: un estudio cruzado, aleatorizado y controlado con placebo
    (Universidad de Murcia: servicio de publicaciones, 2025) Zago, Julio; Santos, Francisco Valdez; Vieira, Paulo, J.C; Rondinel, Tatiana; Diefenthaeler, Fernando; Machado, Sergio; Aprigliano, Vicente; Silva, Weder Alves; Inacio, Pedro Augusto; Sá Filho, Alberto; Chiappa, Gaspar R.; Sin departamento asociado
    Despite the positive effects of photobiomodulation (PBM) on muscle behavior, its effects on exercise tolerance and reactive hyperemia (RH) are poorly understood. Objective: assess the acute effects of PBM with 904 and 660, nm wavelengths irradiated at the forearm flexor muscles on exercise tolerance through the analysis of RH and muscle activation. This preliminary, double-blind, placebo-controlled crossover trial was performed with 11 healthy participants. We randomly applied PBM 904nm, PBM 660nm, and placebo at six different points at the dominant flexor muscle area. The placebo group received the stimulation at the same points with a turned-off device. RH was assessed by measuring forearm blood flow which was calculated using the peak blood flow after the 5-min occlusion with the technique of venous occlusion plethysmography. Electromyography was assessed through surface electrodes on three flexor forearm muscles. The root mean square (RMS) and median frequency (MDF) were plotted at 25, 50, 75, and 100% of the limit of tolerance (Tlim). PBM 660 irradiation significantly increased RH when compared to PBM 904 and placebo. Furthermore, PBM 660 and 904 increased RMS and reduced MDF when compared to placebo. PBM 660 irradiation was superior to 904 and placebo in the increase of RH but the application of both irradiations was similar in the activation of forearm muscles in healthy men. Trial registration: www.ensaiosclinicos.gov.br RBR-7yspdx
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    Photodynamic Therapy, Photobiomodulation and Acetonide Triamcinolone 0.1% in the Treatment of Oral Lichen Planus: A Randomized Clinical Trial
    (MDPI, 2022-12-22) Salinas-Gilabert, Carmen; Gomez Garcia, Francisco; Galera Molero, Fe; Vander Beken, Seppe; Lopez Jornet, Pia; Pons-Fuster López, Eduardo; Dermatología, Estomatología, Radiología y Medicina Física
    Objective: To evaluate the efficacy of photodynamic therapy (PDT) and photobiomodulation (PBM) in the treatment of oral lichen planus (OLP) in comparison with the use of topical corticosteroids. Material and methods: Sixty patients with OLP were randomized to three groups: group 1 photodynamic therapy applied once a week for four sessions, with orabase cream; group 2 low-power laser application with orabase cream; and group 3 inactive laser with triamcinolone acetonide 0.1%. Patient pain was evaluated, and the Thongprasom severity score, the Oral Health Impact Profile-14 (OHIP-14), and the Hamilton anxiety and depression scale at one and three months of follow-up. (ClinicalTrials.gov Identifier: NCT05127083). Results: Pain decreased significantly over time in all groups, though the symptoms relapsed over follow-up at one and three months in group 3. The OHIP-14 score improved significantly in groups 1 and 2 (p < 0.05), and this improvement was maintained after three months. Lesion resolution evaluated by the Thongprasom score at one month showed significant differences between groups 1 and 3 (p = 0.032) and between groups 2 and 3 (p = 0.024). Conclusions: Photodynamic therapy and photobiomodulation once a week for four weeks are safe and non-invasive treatment options, with the important advantage of lacking adverse effects. Further studies are needed to confirm it.