DigitalUM :: Browsing by Subject "PNPs"

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Engineering of microbial cell factories for production of plant-based natural products
(Elsevier, 2021) Gallego Jara, Julia; Lozano Terol, Gema; Sola Martínez, Rosa Alba; Cánovas Díaz, Manuel; Diego Puente, Teresa de; Bioquímica y Biología Molecular B e Inmunología; Facultades de la UMU::Facultad de Medicina
Biotechnology has become a promising alternative to produce highly valuable products. Production using microorganisms competes with chemical synthesis and extraction from natural sources, leading to cheaper and more sustainable production. To produce natural plant products using microorganisms, the development of molecular biology techniques that allow us to genetically and metabolically modify host microorganisms is essential. Thus many biotechnological processes have been developed to obtain terpenes, alkaloids, or polyphenols with interesting applications in the pharmaceutical, food, or cosmetic industries. The increase in our knowledge regarding the metabolism of host organisms, together with the continuous development of genetic and metabolic engineering techniques, will allow, in the coming years, biotechnology to be positioned as the main way to obtain high-value plant natural products.