Browsing by Subject "One Health"

Now showing 1 - 5 of 5
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    A systematic review and meta-analysis of the serological diagnosis of Toxoplasma gondii infection highlight the lack of a One Health integrative research
    (Elsevier, 2023-01-10) Huertas López, Ana; Álvarez García, Gema; Sánchez Sánchez, Roberto; Cantos Barreda, Ana; Ibáñez López, Francisco José; Martínez Subiela, Silvia; Cerón Madrigal, José Joaquín; Martínez-Carrasco Pleite, Carlos; Sanidad Animal; Facultades de la UMU::Facultad de Veterinaria
    Toxoplasma gondii is a globally distributed food-borne zoonotic parasite with numerous infection sources. The control of this zoonosis requires a One Health response that partially depends on serological monitoring in humans and animals. Herein, a systematic review and a meta-analysis were performed to analyse and compare the transdisciplinary and integrative research under the One Health approach. We searched for articles published between January 1st 2014 and September 5th 2022, focused on the development and evaluation of serological techniques for the diagnosis of T. gondii infection in humans and animals. After an exhaustive search on three scientific databases, a quality assessment was performed on 291 articles by QUADAS-2 tool, and 113 articles were finally selected. A total of 18 variables were extracted and analysed, including bibliometric characteristics, study aims and methodology. Remarkably, none of the studies included in the meta-analysis explicitly quoted the words “One Health”, and only 23.9% of them alluded to the principles underlying the One Health approach; in particular, none were conducted by physician-only teams, with the majority of these studies involving interdisciplinary research teams, followed by veterinarians and by non-physician or non-veterinarian researchers. The One Health approach followed in the serodiagnosis of T. gondii still needs further integration among scientific disciplines, which is essential to design effective control strategies.
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    Are future teachers involved in contributing to and promoting the reduction of massive waste generation?
    (2024-09-03) García-Fortes, María Ángeles; Ortega-Lasuen, Unai; Esteve-Guirao, Patricia; Barrutia, Oihana; Ruiz-Navarro, Ana; Zuazagoitia, Daniel; Valverde-Pérez, Magdalena; Díez López, José Ramón; Banos-González, Isabel; Didáctica de las Ciencias Experimentales
    Massive waste generation linked to overconsumption is considered one of the most significant socio-ecological issues today, becoming a challenge for health and well-being and a barrier to achieving sustainability. Education is key to raising awareness and involving citizens in the adoption of responsible consumption habits, facilitating the recognition of the relationship between our daily activities and the production of waste. The aim of this exploratory study is to analyse the perceptions and commitments of future secondary school teachers (FTs) toward this issue and to explore the educational approaches they propose to address it in the classroom (n = 138). In this work, a mixed-methods approach was used based on quantitative and qualitative data collected through a questionnaire. The results show that FTs have difficulties in recognising the different factors involved in the problem of massive waste generation. However, they incorporate the health and ecological vision, which is close to the holistic vision of the One Health approach. The majority of them take personal responsibility for the problem, although they opt for low-effort options. Regarding the educational proposals they design, only a minority can do it following a commitment-oriented approach.
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    El enfoque de una salud (One health) en la investigación oncológica.
    (Universidad de Murcia, Servicio de Publicaciones., 2025) Reyes Villarreal, Mariangela; Fuente Cortéz, Beatriz Elizabeth de la; Vidal Gutiérrez , Oscar; Sin departamento asociado
    El enfoque para abordar los desafíos de salud global esbozado en el proyecto One Health (Una Salud) ha contribuido a la comprensión de la etiopatogenia de las enfermedades oncológicas y a la prevención de los factores asociados susceptibles de ser modificados. La colaboración interdisciplinaria es fundamental en la lucha contra la creciente incidencia de cáncer a nivel mundial y debe ser fomentada por la comunidad científica, por los organismos promotores de la salud y por los Estados.
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    Retos éticos y jurídicos de la restauración de la naturaleza : enfoque One Health y protección de la biodiversidad.
    (Universidad de Murcia, Servicio de Publicaciones., 2024) Lofaro, Giuseppina
    “One Health” abarca un enfoque transdisciplinario de la salud y una mayor colaboración holística entre sectores para abordar los riesgos emergentes y crear las condiciones para una resiliencia transformadora. El enfoque One Health ha asumido un papel clave también en respuesta a otras emergencias zoonótico, de salud pública. Él debería estar la solución adecua­da para promover, apoyar y fortalecer acciones y estrategias inter­disciplinarias e intersectoriales que aborden no sólo prevención de enfermedades, pero también conservación de la biodiversidad, cambio el clima, el desarrollo sostenible y la res­iliencia de la salud humana. Construir perspectivas de futuro desde una perspectiva Ún­ica Sanidad necesita capacidad, entre los interesados de la salud, para incorporar dimensiones salud ambiental con integración de Plataformas nacionales One Health; gobernancia de integración es fundamental para simplificar la respuesta a nivel local para cogestionar salud huma­na, animal y ambiental. La óptica es reducir la posibilidad de prevalencia y futuros brotes e contribuir a un planeta más saludable y sostenible.
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    A systematic review and meta-analysis of the validation of serological methods for detecting anti-Toxoplasma gondii antibodies in humans and animals
    (Elsevier, 2024-03-21) Huertas López, Ana; Cantos Barreda, Ana; Sánchez Sánchez, Roberto; Martínez-Carrasco Pleite, Carlos; Martínez Subiela, Silvia; Cerón Madrigal, José Joaquín; Ibáñez López, Francisco Javier; Álvarez García, Gema; Facultades, Departamentos, Servicios y Escuelas::Departamentos de la UMU::Sanidad Animal; Sanidad Animal
    Toxoplasma gondii is a paradigmatic zoonotic parasite from the One Health perspective, since it is broadly distributed and virtually infects all warm-blooded species. A wide variety of serological techniques have been developed to detect T. gondii infection in humans and animals. Our aim was to describe and compare the main characteristics of these serological tests and validation processes and to critically analyze whether these tests meet the standards required to ensure an accurate serological diagnosis. The current systematic review and metaanalysis included 134 studies that were published from 2013 to 2023. QUADAS 2 tool was used to evaluate the quality of the included studies. A total of 52 variables related to the characteristics of the techniques and analytical and diagnostic validation parameters were studied. A wider panel of tests was developed for humans, including techniques exclusively developed for humans that involve costly equipment and the measurement of different Ig isotypes that are considered biomarkers of congenital toxoplasmosis. Studies conducted in humans frequently employed commercial techniques as reference tests, measured different immunoglobulin isotypes with a predominance for IgG (>50%) and discriminated between acute and chronic infections. In animals, the most commonly used reference techniques were in-house tests, which almost exclusively detected IgG. Common limitations identified in a large number of studies were some misunderstandings of the terms “gold standard” and “reference test” and the absence of information about the negative and positive control sera used or the exact cutoff employed, which were independent of the quality of the study. There is a lack of analytical validation, with few evaluations of cross-reactivity with other pathogens. Diagnostic odds ratio values showed that indirect ELISA based on native or chimeric antigens performed better than other tests. The reproducibility of serological test results in both humans and animals is not guaranteed due to a lack of relevant information and analytical validation. Thus, several key issues should be considered in the future, including interlaboratory ring trials.