Browsing by Subject "Olfactory bulb"

Now showing 1 - 2 of 2
  • Thumbnail Image
    Publication
    Open Access
    Developmental anatomy of the primary olfactory pathway in the opossum Monodelphis domestica
    (Murcia : F. Hernández, 1997) Chuah, M.I.; Tennent, R.; Teague, R.
    It has been shown in previous studies that the marsupial central nervous system is born at a relatively immature state. Although olfaction is thought to play a role in guiding the locomotion of the newborn, the cellular substrates on which this notion is based have not been systematically investigated. This review article surnmarises the anatomical development of the primary olfactory pathway in the postnatal Monodelphis. The olfactory epithelium and bulb appear morphologically immature at birth although some of the olfactory neurons are shown to express olfactory marker protein. The olfactory tissues subsequently undergo a rapid sequence of developmental events during the first two postnatal weeks. The evidence shows that the marsupial and eutherian olfactory system share a similar temporal sequence of developmental processes although the former proceeds at a lag time of about 10-14 days compared to that of mice (using the date of birth as a common reference point). Much physiological and behavioral studies remain to be done before we can be certain about the time at which full functionai maturity is attained in this system.
  • Thumbnail Image
    Publication
    Open Access
    Responses of the astroglia in sensory deprived olfactory bulb of developing rats
    (Murcia : F. Hernández, 1991) Martinez Garcia, Ma del Carmen; Cuervas-Mons, M.; Latorre Macarron, Emilia; Bullon Sopelana, Ma Manuela; Gayoso Rodriguez, Manuel J.
    The effects of ~rnilateral olfactor!, depri\,ation on tlie glial population during the olf~lctory h~llh tle\,clopmcnt lin\je hecn sturliecl. The lack of sensor! stimulation has hcen founcl to he related to an increase in gliofihril1;rry acirl protein (GFAP) in the tliree la!ers of tlic rlzprivcd bulbs. This increase is due to the lli~liern umber of aitrocytes in tlie depri\-ecl hulh. \vliicli is m~ ~ cml io re noticeable in the plcxifo~ml ayer than in tlic other t\jlo. together with :I Ii!.pertrol7li! of the rcacti\e irstrocytes resulting in an increase in tlie n~lmher ancl thickness of their prolongation\. Our results clcmonst~.ate that scnsory olfactor! depri\,ntion acts as other noxius agents on the CNS. causing gliosis in the olfactory hulb. This gliwis is revcalerl h!' astrr)c!,tic liyperplasia allcl Iiyp~rtropli!~.